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4 hours ago · Palo Alto, California. / 37.42917°N 122.13806°W / 37.42917; -122.13806. Palo Alto ( / ˌpæloʊ ˈæltoʊ / PAL-oh AL-toh; Spanish for 'tall stick') is a charter city in the northwestern corner of Santa Clara County, California, United States, in the San Francisco Bay Area, named after a coastal redwood tree known as El Palo Alto .