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1. link.springer.com › referenceworkentry › 10Expected Outcomes for Acute PE Management | SpringerLink

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   Jul 3, 2024 · Anticoagulant use in humans, in the form of intravenous heparin, began in 1935 and was routine by the 1940s in treatment of patients with venous thromboembolism (Galanaud et al. 2013 ). Despite this revolutionary development in the management of deep venous thrombosis and pulmonary embolism, immobilization was still recommended.

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