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The Lester lab uses techniques at the intersection of biophysics, single-molecule imaging, chemistry, mouse genetics, and neuroscience to understand the biophysical basis of ligand-gated ion channels including the nicotinic acetylcholine receptor.
Henry A Lester. In Parkinson's Disease (PD) there is widespread neuronal loss throughout the brain with pronounced degeneration of dopaminergic neurons in the SNc, leading to bradykinesia,...
Henry A. Lester, Ph. D., is Bren Professor at the California Institute of Technology, where he has spent his entire teaching career. He has written more than 300 scientific papers and holds seven patents on drugs and the brain, including topics such as nicotine addiction and Parkinson’s disease.
Research. Our lab research focus is primarily on understanding the pathophysiology of nicotine addiction, the world's largest preventable cause of death. We are studying complex neural processes at several appropriate levels: the genes, the receptor proteins, the effects on neurons, the organization of neurons in circuits, the resulting ...
Henry A. Lester. Professor of Biology and Biological Engineering, Caltech. Verified email at caltech.edu. Title. Sort. Sort by citations Sort by year Sort by title. Cited by. Cited by.
Dec 15, 2021 · Professor of Biology Henry Lester has been named as a fellow of the National Academy of Inventors (NAI).
Jun 6, 2024 · Henry Allen Lester. Bren Professor of Biology. Applied a wide range of techniques, including flash-activated molecules, mutagenesis, and incorporation of unnatural sidechains, to the study of the structure and function of ion channels and neurotransmitter receptors.
