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What does CA 19-9 mean?
What does CA 19-9 mean in pancreatic cancer?
Can a high CA 19-9 level be a sign of cancer?
What is a CA 19-9 blood test?
Detect early-stage cancer
- A CA 19-9 test is one of a panel of tests used to detect early-stage cancer. As a tumor marker that’s produced by cancer and other cells in the body, CA 19-9 provides important clues about the presence and progression of cancer. The CA 19-9 blood test is used to help support a patient’s cancer diagnosis and assess cancer treatment.
www.cancercenter.com/diagnosing-cancer/diagnostic-procedures/tumor-markers/ca-19-9
Jun 7, 2023 · CA 19-9 is a protein that may indicate certain cancers, especially pancreatic cancer. Learn how the test is done, what the normal range is and how to interpret the results.
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- CA 27.29
- What is a CA 19-9 blood test?
- What is it used for?
- Why do I need a CA 19-9 test?
- What happens during a CA 19-9 blood test?
- Will I need to do anything to prepare for the test?
- Are there any risks to the test?
- What do the results mean?
- Is there anything else I need to know about a CA 19-9 test?
- References
- Related Health Topics
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A CA 19-9 test measures the amount of a protein called CA 19-9 (cancer antigen 19-9) in a sample of your blood. CA 19-9 is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in your body.
Healthy people can have small amounts of CA 19-9 in their blood. High levels of CA 19-9 are often a sign of pancreatic cancer. But high levels can also be a sign of other types of cancer or certain conditions that aren't cancer. For example, gallstones and cirrhosis of the liver can cause high CA 19-9 levels.
Because high levels of CA 19-9 can mean different things, the test is not used by itself to screen for or diagnose cancer or other diseases. But it can help monitor your cancer and check how well your treatment is working.
Other names: cancer antigen 19-9, carbohydrate antigen 19-9, CA 199 measurement, CA 19-9 radioimmunoassay (RIA)
CA 19-9 blood tests may be used to:
•Monitor certain types of cancer and cancer treatment. CA 19-9 levels often go up as cancer grows and go down as tumors shrink.
•Help predict how cancer may behave over time.
•Check whether cancer has returned after treatment.
•Help diagnose certain cancers and other diseases when used with other tests.
Some people do not make CA 19-9 even when they have a cancer that usually produces high levels of CA 19-9. For these people, a CA 19-9 tumor marker test is not useful.
You may need a CA 19-9 blood test if you've been diagnosed with pancreatic cancer or another type of cancer that causes high CA 19-9. These include cancers of the:
•Bile duct
•Colon and rectum
•Stomach
•Ovaries
•Bladder
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
Usually, you don't need any special preparations for a CA 19-9 blood test. But ask your provider to be sure. If you take certain vitamins, you may need to stop them before the test.
There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.
If you're being treated for cancer, you may be tested several times during your treatment. Your provider will look at all your test results to see how your CA 19-9 levels have changed. Your results may show:
•Your levels of CA 19-9 are increasing. This may mean your tumor is growing, and/or your treatment is not working. More tests are usually needed to find out for sure.
•Your levels of CA 19-9 are decreasing. This may mean your tumor is shrinking and your treatment is working.
•Your levels of CA 19-9 have stayed the same. This may mean your disease is stable and hasn't gotten better or worse.
•Your CA 19-9 levels decreased after treatment, but increased later. This may mean your cancer has come back or grown. You'll need more tests to check whether cancer is really causing the higher level of CA 19-9.
If you don't have cancer but your test results show a high level of CA 19-9, you may not a health problem that needs treatment. Healthy people can have high CA 19-9 levels. But high levels may be a sign of a condition, such as:
Labs use different methods to measure the amount of CA 19-9 in your blood sample. The test method can affect your results. If you're having regular tests to monitor cancer, it's important to have your tests done the same way, and usually in the same lab. This allows your provider to compare your results over time. Your test report usually says what...
1.Allina Health [Internet]. Minneapolis: Allina Health; Cancer antigen 19-9 Measurement; [cited 2022 Aug 11]; [about 3 screens]. Available from: https://account.allinahealth.org/library/content/49/150320
2.American Cancer Society [Internet]. Atlanta: American Cancer Society Inc.; c2022. Pancreatic Cancer Stages; [updated 2017 Dec 18; cited 2022 Aug 11]; [about 5 screens]. Available from: https://www.cancer.org/cancer/pancreatic-cancer/detection-diagnosis-staging/staging.html
3.Cancer.Net [Internet]. Alexandria (VA): American Society of Clinical Oncology; 2005–2022. Pancreatic Cancer: Diagnosis; [updated 2021 Sep; cited 2022 Aug 11]; [about 5 screens]. Available from: https://www.cancer.net/cancer-types/pancreatic-cancer/diagnosis
4.Hinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Cancer Tumor Markers (CA 15-3 [27, 29], CA 19-9, CA-125, and CA-50); 121 p.
5.Johns Hopkins Medicine [Internet]. Johns Hopkins Medicine; Health Library: Pancreatic Cancer Diagnosis; [cited 2022 Aug 11]; [about 3 screens]. Available from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/pancreatic-cancer/pancreatic-cancer-diagnosis
6.LabCorp [Internet]. Burlington (NC): Laboratory Corporation of America® Holdings; c2022. Patient Test Information: Cancer Antigen 19-9; [cited 2022 Sep 6]; [about 5 screens]. Available from: https://www.labcorp.com/help/patient-test-info/cancer-antigen-19-9
A CA 19-9 test measures a protein that can be a sign of pancreatic cancer and other types of cancer. Learn how the test is done, what the results mean, and what conditions can affect the test.
CA19-9 is a protein found on the surface of some cancer cells, especially pancreatic cancer. Learn how a CA19-9 test is done, what the results mean and what happens if a change or abnormality is found.
CA 19-9 is a protein that can help diagnose cancers in the colon, pancreas, stomach, or bile duct. It can also indicate noncancerous conditions, such as gallstones or pancreatitis.
Dec 12, 2020 · CA 19-9 is an adjunct tumor marker used in the diagnosis of CCA. CA 19-9 > 100 U/mL on a malignant biliary stricture background without bacterial cholangitis suggests perihilar CCA. Its diagnostic value has also been evaluated in patients with Primary Sclerosing Cholangitis, which is a significant risk factor for CCA.
- Tsinrong Lee, Thomas Zheng Jie Teng, Vishal G Shelat
- 10.4240/wjgs.v12.i12.468
- 2020
- 2020/12/12
CA19-9 is a type of antigen released by pancreatic cancer cells that can be measured by a blood test. Learn how the test is done, what the results mean and what other conditions can cause high CA19-9 levels.
May 6, 2021 · Studies also show that CA 19-9 levels may correlate with tumor burden, disease recurrence, and response to treatment. Thus, CA 19-9 is a better marker for advanced pancreatic neoplasms than...
