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Coniine is a poisonous chemical compound, an alkaloid present in and isolable from poison hemlock (Conium maculatum), where its presence has been a source of significant economic, medical, and historico-cultural interest; coniine is also produced by the yellow pitcher plant (Sarracenia flava), and fool's parsley (Aethusa cynapium).
Coniine is a piperidine alkaloid found in Poison Hemlock (Conium maculatum) that acts as an antagonist to nicotinic acetylcholine receptors, affecting neuromuscular transmission and leading to symptoms such as drowsiness, burning of the mouth, paralysis, and even death in humans. AI generated definition based on: Synaptic Transmission, 2019.
Nov 14, 2017 · Abstract. Coniine, a polyketide-derived alkaloid, is poisonous to humans and animals. It is a nicotinic acetylcholine receptor antagonist, which leads to inhibition of the nervous system, eventually causing death by suffocation in mammals.
- Hannu Hotti, Heiko Rischer
- 10.3390/molecules22111962
- 2017
- Molecules. 2017 Nov; 22(11): 1962.
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conine has a nicotine-like action in first stimulating and then depressing autonomic ganglia, and a curare-like effect in paralysing the motor nerve endings to the skeletal muscles.
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Codeine is the most commonly used opioid medication in Canada. It is used to relieve cough and mild to moderate pain but it is addictive when used in high doses and used over a long period of time. The more you use codeine, the more your health is affected.
