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  1. Feb 6, 2024 · Psychedelic and dissociative drugs can temporarily alter a person’s mood, thoughts, and perceptions. Among other health effects and safety concerns, people who use these substances report feeling strong emotions ranging from bliss to fear and experiencing vast changes in how they perceive reality.

  2. Over 6,500 completed the section on self-treatment of psychiatric conditions and emotional distress with psychedelics. 72% were male, 25% female with 2% identifying as non-binary/other. In this report we highlight some of the most noteworthy findings.

  3. Classic psychedelics produce altered states of consciousness that individuals often interpret as meaningful experiences. Across a number of human studies, when the participant-rated intensity of the overall drug effects are statistically controlled for, certain subjective effects predict therapeutic and other desirable outcomes.

    • David B. Yaden, Roland R. Griffiths
    • 2021
    • Enduring Benefits
    • Set and Setting
    • Cautious Optimism

    Research on the potential benefits of psychedelic drugs has a long but interrupted history. Drugs in this class—including psilocybin, mescaline (peyote), DMT and LSD—act on the serotonin 2A receptor, producing hallucinogenic experiences. In the mid-20th century, scientists began studying whether these drugs could treat problems such as addiction an...

    Some research suggests that nonclinical use of psychedelic drugs is even associated with better mental health among the general population. Peter Hendricks, PhD, a professor of psychology at the University of Alabama at Birmingham, and colleagues gathered data from the National Survey on Drug Use and Health and found that people who reported using ...

    While researchers are excited about the possibilities of psychedelics, they’re also circumspect. The drugs themselves are quite safe, says Hendricks. “We know of no data that psychedelics are addictive, and there are no withdrawal symptoms—but they can be used in a dangerous or inappropriate context,” he says. People can become frightened and disor...

  4. Oct 20, 2020 · Studies focusing on user segments with problematic usage patterns tend to find that psychedelics use is negative for mental health, while studies on infrequent users tend to find that psychedelics use is positive for mental health. Conclusion:

    • Petter Grahl Johnstad
    • Nordisk Alkohol Nark. 2021 Feb; 38(1): 35-49.
    • 10.1177/1455072520963787
    • 2021/02
  5. Aug 8, 2023 · Psychoactive drugs are substances that, when taken in or administered into one's system, affect mental processes, e.g. perception, consciousness, cognition or mood and emotions. Psychoactive drugs belong to a broader category of psychoactive substances that include also alcohol and nicotine.

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  7. Sep 14, 2020 · Current behavioural and neuroimaging data show that psychedelics induce their psychological effects (Box 1) primarily via 5-hydroxytryptamine (serotonin) type 2A (5-HT 2A) receptor activation and...

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