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1. pubmed.ncbi.nlm.nih.gov › 34617510Modulation of fracture healing by the transient accumulation ...

   pubmed.ncbi.nlm.nih.gov › 34617510

   Oct 7, 2021 · Our findings thus demonstrate that senescent cells accumulate transiently in the murine fracture callus and, in contrast to the skin, their clearance does not impair but rather improves fracture healing. Keywords: bone; callus; fracture; medicine; mouse. © 2021, Saul et al.

   • Author: Dominik Saul, Dominik Saul, David G Monroe, Jennifer L Rowsey, Robyn Laura Kosinsky, Stephanie J Vos...

   • Publish Year: 2021

2. pubmed.ncbi.nlm.nih.gov › 34017133XCR1+ type 1 conventional dendritic cells drive liver ...

   pubmed.ncbi.nlm.nih.gov › 34017133

   We identified a significant pathology-associated increase in hepatic conventional dendritic cells (cDCs) and further defined their source as NASH-induced boost in cycling of cDC progenitors in the bone marrow.

   • Author: Aleksandra Deczkowska, Aleksandra Deczkowska, Eyal David, Pierluigi Ramadori, Dominik Pfister, Micha...

   • Publish Year: 2021

3. pubmed.ncbi.nlm.nih.gov › 33313996Comparative Efficacy of Dual and Single Initiation ... - PubMed

   pubmed.ncbi.nlm.nih.gov › 33313996

   For reduction of HbA1c, weight, and SBP in patients uncontrolled on metformin, add-on dual AHAs showed greater improvement compared to single AHAs. These findings can further inform the treatment of T2DM patients uncontrolled on metformin.

   • Author: Dominik Lautsch, Adnan Alsumali, Euan McLeod, Yuting Kuang, Jing He, Rajpal Singh, Arianna Nevo, Urs...

   • Publish Year: 2021

4. www.nature.com › articles › s41586/021/03362-0NASH limits anti-tumour surveillance in immunotherapy-treated ...

   www.nature.com › articles › s41586/021/03362-0

   Mar 24, 2021 · Preventive anti-PD1 treatment was strongly associated with the pro-tumorigenic immunosuppressive ICF signature (for example, Ifng, Tnf, Stat3, Tgfb1 ), capturing the traits of T cell exhaustion...

   • Author: Dominik Pfister, Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol, Olivier Govaere, Matthias Pin...

   • Publish Year: 2021

5. www.nature.com › articles › s41592/021/01326-wOME-NGFF: a next-generation file format for expanding ...

   www.nature.com › articles › s41592/021/01326-w

   Nov 29, 2021 · Abstract. The rapid pace of innovation in biological imaging and the diversity of its applications have prevented the establishment of a community-agreed standardized data format.

6. en.wikipedia.org › wiki › Golden_Gate_CapitalGolden Gate Capital - Wikipedia

   en.wikipedia.org › wiki › Golden_Gate_Capital

   • Cached

   The firm was founded in 2000 by former investment professionals from private equity firm Bain Capital and its affiliate, Bain & Company, led by former Bain Capital partner David Dominik.

7. People also ask

   Are hepatic conventional dendritic cells induced by Nash?

   • We identified a significant pathology-associated increase in hepatic conventional dendritic cells (cDCs) and further defined their source as NASH-induced boost in cycling of cDC progenitors in the bone marrow.

   XCR1+ type 1 conventional dendritic cells drive liver ... - PubMed

   pubmed.ncbi.nlm.nih.gov/34017133/

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   Does cdkn2aluc induce transient senescent cell accumulation during callus formation?

   • Then, using a genetic mouse model ( Cdkn2aLUC) containing a Cdkn2aInk4a -driven luciferase reporter, we demonstrated transient in vivo senescent cell accumulation during callus formation.

   Modulation of fracture healing by the transient accumulation of senesce…

   pubmed.ncbi.nlm.nih.gov/34617510/

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   Do anti-pd1-treated Nash mice have non-proliferative T cells?

   • CD8 + PD1 + T cells were non-proliferative in anti-PD1-treated NASH mice; this result was supported by in vitro experiments, in which anti-PD1 treatment led to increased T cell numbers in the absence of proliferation (Extended Data Fig. 6l, m ).

   NASH limits anti-tumour surveillance in immunotherapy-treated HCC

   www.nature.com/articles/s41586-021-03362-0

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   How does anti-PD1 immunotherapy affect PD1 expression in Nash mice?

   • Thus, upon anti-PD1 immunotherapy in NASH mice, CD8 + PD1 + T cells accumulated to high numbers in the liver, revealing a resident-like T cell character with increased expression of CD44, CXCR6, EOMES and TOX and low levels of CD244 expression, but lacking expression of TCF1/TCF7, CD62L, TBET, and CD127 (Extended Data Fig. 6p–u ).

   NASH limits anti-tumour surveillance in immunotherapy-treated HCC

   www.nature.com/articles/s41586-021-03362-0

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8. journals.sagepub.com › doi › fullRelationship difficulties and “technoference” during the ...

   journals.sagepub.com › doi › full

   May 4, 2022 · Our results corroborate research showing that people spend more time using technology when experiencing greater stressors (e.g. feeling worried, when feeling alone, or bored; Al-Saggaf et al., 2019; Drouin et al., 2018; Juvonen et al., 2021) and is in line with the stress-spillover hypotheses (Neff & Karney, 2017), whereby external stressors ...