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  1. There are several theories about how IV vitamin C may help treat COVID-19: Very high vitamin C levels may create free radicals that destroy viruses and bacteria. Our body’s cells have defenses against these free radicals, but viruses do not.

  2. March 13, 2020 – The Linus Pauling Institute is closely watching the clinical trials with intravenous (IV) vitamin C and COVID-19-related pneumonia with great interest. However, there currently are no available data to show vitamin C can prevent or successfully treat COVID-19 infections.

  3. Dec 7, 2020 · This literature review focuses on vitamin C deficiency in respiratory infections, including COVID-19, and the mechanisms of action in infectious disease, including support of the stress response, its role in preventing and treating colds and pneumonia, and its role in treating sepsis and COVID-19.

    • Patrick Holford, Anitra C Carr, Thomas H Jovic, Thomas H Jovic, Stephen R Ali, Stephen R Ali, Iain S...
    • 10.3390/nu12123760
    • 2020
    • Nutrients. 2020 Dec; 12(12): 3760.
  4. Therefore, the Linus Pauling Institute's intake recommendation of 400 mg/day of vitamin C for generally healthy adults takes into account the currently available epidemiological, biochemical, and clinical evidence, while acknowledging the extremely low toxicity of vitamin C and the incomplete information regarding optimum intake.

  5. Feb 3, 2023 · Linus Pauling, who was awarded the Nobel Prize in Chemistry, suggested that a high dose of vitamin C (l-ascorbic acid) might work as a prevention or treatment for the common cold. Vitamin C therapy was tested in clinical trials, but clear evidence was not found at that time.

  6. May 19, 2022 · According to the famous 1970s Linus Pauling's theory, vitamin C intake help to reduce susceptibility to respiratory tract infections. The theory has remained controversial over the years; however, the sales of vitamin C have increased substantially in the US market ( 13 ).

  7. May 19, 2022 · According to the famous 1970s Linus Pauling's theory, vitamin C intake help to reduce susceptibility to respiratory tract infections. The theory has remained controversial over the years; however, the sales of vitamin C have increased substantially in the US market ( 13 ).