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What is transitional cell carcinoma (TCC) in dogs?
What is transitional cell carcinoma (TCC)?
Where does TCC come from?
What is transitional cell cancer in dogs?
How do I know if my dog has TCC?
What breeds of dogs have TCC?
Sep 11, 2023 · Transitional Cell Carcinoma (TCC) is a form of bladder cancer that commonly affects older dogs, particularly females. This aggressive cancer originates in the transitional epithelial cells lining the bladder and can also occur in the urethra, kidneys, or prostate.
Transitional cell carcinoma (TCC) is the most common cancerous condition affecting the urinary tract of dogs. Scottish Terriers top the list in terms of breed predisposition. What is TCC? TCC is a malignant tumor that most commonly grows within the urinary bladder.
Oct 6, 2003 · Transitional cell carcinoma (frequently abbreviated to TCC) is a particularly unpleasant malignant tumor of the urinary bladder. This tumor type is also sometimes called urothelial carcinoma. In dogs, it usually arises in the lower neck of the bladder, where it is virtually impossible to surgically remove, and causes a partial or complete ...
- Symptoms.
- Diagnosis.
- Treatment.
- Drug Therapy.
- Other Chemotherapy Drugs.
- Prognosis.
A diagnosis of TCC is suspected when the following symptoms are exhibited: 1. Straining to urinate or urinating small amounts frequently 2. Blood in the urine 3. Inability to urinate (obstructed bladder) These symptoms are not specific for a bladder tumor. Animals with bladder infections or bladder stones may behave the same way. A bladder tumor or...
It is rare that a bladder tumor can be felt by palpating the belly, and most bladder tumors are not seen on abdominal radiographs (x-rays). Some tests your veterinarian may recommend if a bladder tumor is suspected include urinalysis (microscopic examination of a urine sample), ultrasound of the abdomen, biopsy to confirm the diagnosis if a mass is...
Surgery may be a treatment option for cats with TCC, because the tumor tends to involve a part of the bladder that is not essential for bladder control. Surgery is often not a good treatment option for TCC in dogs because the tumor is often located in the neck of the urinary bladder. Surgery in this site may render the dog incontinent (unable to co...
Drug therapy is the most common treatment for TCC. Up to 40% of dogs with TCC may have a response to medical therapy, although that response is almost always partial. Although not all tumors shrink in response to therapy, another positive response is a decrease in the growth rate of the tumor. Medications that may have some effect against TCC in do...
Mitoxantrone, carboplatin and doxorubicin are more traditional chemotherapy drugs. The two equally important goals of chemotherapy are to control the tumor for as long as possible and maintain a good to excellent quality of life throughout the duration of treatment. Occasionally, radiation therapy may be recommended to help relieve some of the clin...
Ultimately, TCC is a fatal disease. The tumor will most frequently grow to obstruct either the urethra or the ureters, which can result in kidney failure due to obstruction. There is also the potential for metastasis (tumor spread to a distant site). With treatment, average survival times following diagnosis are between six and nine months. However...
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Jul 1, 2008 · Transitional-cell carcinoma (TCC) is the most common of these malignancies and involves the bladder and/or the urethra. Affected dogs tend to be older and smaller in size (<10 kg). There may be a gender predilection, with females being more commonly affected, although this finding has not been consistent in all studies.
Transitional cell carcinoma (TCC) is the most common canine tumor of the bladder and urethra. At this time, the cause of transitional cell carcinoma is not known. Exposure to carcinogenic compounds is suspected to be a contributing factor, but very few specific agents have been identified. TCC is seen more commonly in female dogs than males.
Urinary bladder cancer in dogs is a challenging disease to diagnose, stage, and treat. Invasive transitional cell carcinoma (TCC) is the most common form of canine urinary bladder cancer affecting tens of thousands of dogs worldwide each year, and the prevalence appears to be on the rise.
