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4 days ago · Posthumously, in 2000, Cancer: Evolution to Revolution was awarded a Peabody. His work was nominated for two Emmy's: Outstanding non-fiction special for Lenny Bruce: Swear To Tell The Truth in 1999 [5] and Outstanding achievement in non-fiction programming for Cancer: Evolution to Revolution in 2000 [6]
Jul 4, 2024 · For many cancers, drug resistance evolution represents one of the greatest challenges to the development of curative anticancer therapies. Studies of single-cell heterogeneity have revealed that ...
Jul 16, 2024 · The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve—like cancer and pathogens—defying conventional wisdom. In cancer, it is well known ...
Jul 9, 2024 · For the first time, scientists have provided unbiased estimates of the number of mutations needed for cancers to develop, in a study of more than 7,500 tumours across 29 cancer types. Researchers from the Wellcome Trust Sanger Institute and their collaborators adapted a technique from the field of evolution to confirm that, on average, 1 to 10 driver mutations are needed for cancer to emerge ...
Jul 12, 2024 · Cancer evolution lays the groundwork for predictive oncology. Testing evolutionary metrics requires quantitative measurements in controlled clinical trials. We mapped genomic intratumor ...
Jul 18, 2024 · A resource to evaluate replication timing in lung and breast cancer. To evaluate the dynamics of mutation acquisition during cancer evolution, we first explored the density of mutations across the ...
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Jul 11, 2024 · MD Anderson Research Highlights for July 11, 2024. Featuring discoveries in cancer development and evolution, improving treatment options for Ewing’s sarcoma, breast and lung cancer, and new disease classifications. MD Anderson News Release July 11, 2024. The University of Texas MD Anderson Cancer Center’s Research Highlights provides a ...
