2021
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In biology and other experimental sciences, an in silico experiment is one performed on a computer or via computer simulation software. The phrase is pseudo-Latin for 'in silicon' (correct Latin: in silicio ), referring to silicon in computer chips. It was coined in 1987 as an allusion to the Latin phrases in vivo, in vitro, and in situ, which ...
Oct 27, 2021 · The term ‘ in silico’ refers to computational models that investigate pharmacological hypotheses using methods such as databases, data analysis tools, data mining, homology models, machine ...
Apr 19, 2024 · in silico: [adverb or adjective] in or on a computer : done or produced by using computer software or simulation.
In silico modelling, in which computer models are developed to model a pharmacologic or physiologic process, is a logical extension of controlled in vitro experimentation. It is the natural result of the explosive increase in computing power available to the research scientist at continually decreasing cost.
Nov 15, 2013 · An in silico model to mimic the in vitro rolling, activation, and adhesion of individual leukocytes has been developed by Tang et al. (2007). Developing virtual mitochondria, Cree et al. (2008) have demonstrated how the in silico modeling can assist in predicting the severity of mitochondrial diseases.
- 10.1016/B978-0-12-416002-6.00021-3
- 2014
- Animal Biotechnology. 2014 : 385-404.
Dec 23, 2022 · In this review, we present an overview of the important CADD methods and applications, such as in silico structure prediction, refinement, modelling and target validation, that are commonly used in this area. Keywords: drug discovery, computer-aided drug design, in silico drug design. 1. Introduction.
An in silico clinical trial, also known as a virtual clinical trial, is an individualized computer simulation used in the development or regulatory evaluation of a medicinal product, device, or intervention. While completely simulated clinical trials are not feasible with current technology and understanding of biology, its development would be ...
