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  1. Research on aging is constantly evolving and includes a variety of studies involving genetics, biochemistry, animal models, and human longitudinal studies (NIA, 2011a). According to Jin (2010), modern biological theories of human aging involve two categories.

    • Martha Lally, Suzanne Valentine-French
    • 2021
  2. There are countless theories as to why and how we age, but, until recently, the very definition of aging – senescence – was still uncertain. Here, we summarize the main views of the different models of senescence, with a special emphasis on the biochemical processes that accompany aging.

    • João Pinto da Costa, Rui Vitorino, Gustavo M. Silva, Christine Vogel, Armando C. Duarte, Teresa Roch...
    • 10.1016/j.arr.2016.06.005
    • 2016
    • 2016/08
  3. WHAT IS A THEORY OF AGING? Theories of aging can be divided into two categories: those that answer the question “Why do we age?” and those that address the. question “How do we age?” Only a few broad, overarching theories attempt to explain why we and nearly all living organisms age.

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    • 9
  4. KEY CONCEPTS: Definitions. Chronological Age: Number of years/months/days a person has been alive . Biologic Age: determined by intracellular and molecular processes – how old a person seems. Heterogeneity of Aging: individuals within a species age at different rates; different organs may age at different rates within a single individual.

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  5. Oct 22, 2023 · No one theory is sufficiently able to explain the process of aging, and they often contradict one another. All valid theories of aging must meet three broad criteria: The aging changes that the theory addresses must occur commonly in all members of a humans.

  6. Aging is associated not only with the buildup of metabolic by-products, but also with the dysregulation of regulatory pathways. For example, aging upsets the balance between pro- and anti-inflammatory components, promoting chronic inflammation.

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  8. Nov 1, 2015 · This article will explore several common theories about why and how we age. By understanding current aging theories, clinicians can follow advances in aging research and intelligently address patient questions about life extension therapies and strategies to slow aging. Why do we age?

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