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  1. The most common cancer of the urinary tract in dogs is transitional cell carcinoma (TCC), which is a cancer of the epithelial cells that line the urinary tract. This cancer most commonly occurs in older female dogs (although both males and females can be affected).

  2. Oct 6, 2003 · Transitional cell carcinoma (frequently abbreviated to TCC) is a particularly unpleasant malignant tumor of the urinary bladder. This tumor type is also sometimes called urothelial carcinoma.

    • Etiology
    • Diagnosis
    • Treatment Options
    • Prognosis

    There appear to be both genetic and environmental risk factors for the development of TCC in dogs. In humans, cigarette smoking, exposure to chemicals, use of select medications and chronic inflammatory conditions of the bladder have been associated with an increased risk of bladder tumors. Previous studies have found that dogs exposed to insectici...

    As would be expected, the most common clinical signs are stranguria, hematuria, dysuria and pollakiuria. Rarely is the presenting sign lameness, secondary either to hypertrophic osteopathy or bone metastasis. A tentative diagnosis can be made via identification of a bladder (Photos 1 and 2) or urethral mass (Photo 3) on ultrasound or other imaging,...

    1. Surgery:Given the size and location of these tumors, surgical intervention often is not an option. Tumors in the apex are more amenable to surgical resection; however, there is still a high risk of local recurrence and/or distant metastasis so that surgery is not likely to be curative. Photo 4: A CT scan of urethral TCC extending into the prosta...

    The long-term prognosis for dogs with TCC is considered to be guarded, but with treatment some patients can have a good quality of life for extended periods. Metastatic disease is present in 20 percent of dogs at the time of diagnosis. If dogs have a prolonged survival time, the metastatic rate can be as high as 50 percent to 60 percent. Regional l...

  3. Jun 2, 2022 · Of the different types of lower urinary system cancers in dogs, transitional cell carcinoma (TCC) is by far the most common. It accounts for up to 90% of all bladder tumors. The other 10% consist of many other types of tumors, including: Leiomyosarcoma. Adenocarcinoma.

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  4. Sep 11, 2023 · Transitional Cell Carcinoma (TCC) is a form of bladder cancer that commonly affects older dogs, particularly females. This aggressive cancer originates in the transitional epithelial cells lining the bladder and can also occur in the urethra, kidneys, or prostate.

  5. Urinary bladder cancer in dogs is a challenging disease to diagnose, stage, and treat. Invasive transitional cell carcinoma (TCC) is the most common form of canine urinary bladder cancer affecting tens of thousands of dogs worldwide each year, and the prevalence appears to be on the rise.

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  7. Transitional cell carcinoma (TCC) is a cancerous tumor most commonly found in the urinary bladder and the urethra. It is most often seen in older small-breed dogs such as Scottish terriers, West Highland white terriers, dachshunds, and Shetland sheepdogs and is rarely identified in cats.

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