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DOI: 10.1111/j.1525-139X.2007.00308.x Abstract The discovery of fibroblast growth factor 23 (FGF23), a novel bone-derived hormone that inhibits phosphate reabsorption and calcitriol production by the kidney, has uncovered primary regulatory pathways and new systems biology governing bone mineralization, vitamin D metabolism, parathyroid gland function and renal phosphate handling.
May 15, 2012 · FGF23 is a bone-derived hormone that regulates systemic phosphate homeostasis, vitamin D metabolism and α-Klotho expression through a novel bone-kidney axis. FGF23 inhibits renal tubular reabsorption of phosphate through mechanisms independent of PTH as well as reduces circulating 1, 25 (OH) (2)D through its dual effects to suppress Cyp27b1 ...
L Darryl Quarles The P1 and P2 promoters of the Cbfa1/Runx2 gene produce Type I and II mRNAs with distinct complex 5'-untranslated regions, respectively designated UTR1 and UTR2.
Darryl Quarles (as Darryl J. Quarles) Michael Green; Show all; Screenplay: Darryl Quarles (as Darryl J. Quarles) Peter Gaulke; Gerry Swallow; Production country: USA; Production company: New Regency Productions Inc. Runteldat Entertainment; The Firm Films; Classification: Allowed from age 11: Dialogue: English; Swedish release: 2002-06-14
Aline Martin 1 , L Darryl Quarles. Affiliation 1 Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA. PMID: ...
L Darryl Quarles 1 Affiliation 1 Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. quarl001@mc.duke.edu; PMID: 12952909 ...
L Darryl Quarles Pkd1 encodes PC1, a transmembrane receptor-like protein, and Pkd2 encodes PC2, a calcium channel, which interact to form functional polycystin complexes that are widely expressed ...
