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   What is insulin resistance?

   • Insulin resistance is a complex condition in which your body does not respond as it should to insulin, a hormone your pancreas makes that’s essential for regulating blood sugar levels. Several genetic and lifestyle factors can contribute to insulin resistance. Learn about insulin resistance and what insulin does in your body.

   Insulin Resistance: What It Is, Causes, Symptoms & Treatment

   my.clevelandclinic.org/health/diseases/22206-insulin-resistance

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   What causes insulin resistance?

   • The two main factors that seem to contribute to insulin resistance are excess body fat, especially around your belly, and a lack of physical activity. People who have prediabetes and Type 2 diabetes usually have some level of insulin resistance. People with Type 1 diabetes can also experience insulin resistance. How common is insulin resistance?

   Insulin Resistance: What It Is, Causes, Symptoms & Treatment

   my.clevelandclinic.org/health/diseases/22206-insulin-resistance

   See all results for this question

   What happens if you have insulin resistance?

   • If you have insulin resistance, but your pancreas can increase insulin production to keep your blood sugar levels in range, you won’t have any symptoms. However, over time, insulin resistance can get worse, and the cells in your pancreas that make insulin can wear out.

   Insulin Resistance: What It Is, Causes, Symptoms & Treatment

   my.clevelandclinic.org/health/diseases/22206-insulin-resistance

   See all results for this question

2. my.clevelandclinic.org › health › diseasesInsulin Resistance: What It Is, Causes, Symptoms & Treatment

   my.clevelandclinic.org › health › diseases

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   Insulin resistance is a complex condition in which your body does not respond as it should to insulin, a hormone your pancreas makes that’s essential for regulating blood sugar levels. Several genetic and lifestyle factors can contribute to insulin resistance.

3. www.webmd.com › diabetes › insulin-resistance-syndromeInsulin Resistance: Symptoms, Causes, Tests, and Treatment

   www.webmd.com › diabetes › insulin-resistance-syndrome

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   Apr 22, 2024 · Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin, a hormone made by your pancreas that helps manage your blood glucose (blood sugar)....

4. www.mayoclinic.org › diseases-conditions › obesityWhat is insulin resistance? A Mayo Clinic expert explains

   www.mayoclinic.org › diseases-conditions › obesity

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   Aug 18, 2022 · To understand insulin resistance, often referred to as prediabetes, let's first talk about what insulin does. When you eat food, your body converts that food into dietary sugars. Insulin is a hormone released by the pancreas that tells your cells to open up to that sugar and convert it into energy.

5. en.wikipedia.org › wiki › Insulin_resistanceInsulin resistance - Wikipedia

   en.wikipedia.org › wiki › Insulin_resistance

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   Insulin resistance (IR) is a pathological condition in which cells either fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia. Insulin is a hormone that facilitates the transport of glucose from blood into cells, thereby reducing blood glucose (blood sugar).

6. www.niddk.nih.gov › prediabetes-insulin-resistanceInsulin Resistance & Prediabetes - NIDDK

   www.niddk.nih.gov › prediabetes-insulin-resistance

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   What is insulin resistance? Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin and can’t easily take up glucose from your blood. As a result, your pancreas makes more insulin to help glucose enter your cells.

7. diabetes.org › health-wellness › insulin-resistanceInsulin Resistance and Diabetes | ADA

   diabetes.org › health-wellness › insulin-resistance

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   People with insulin resistance, also known as impaired insulin sensitivity, have built up a tolerance to insulin, making the hormone less effective. As a result, more insulin is needed to persuade fat and muscle cells to take up glucose and the liver to continue to store it.

8. www.ncbi.nlm.nih.gov › books › NBK507839Insulin Resistance - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK507839

   Sep 9, 2020 · Insulin resistance, identified as an impaired biologic response to insulin stimulation of target tissues, primarily involves liver, muscle, and adipose tissue. Insulin resistance impairs glucose disposal, resulting in a compensatory increase in beta-cell insulin production and hyperinsulinemia.