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  1. Feb 23, 2023 · Elexacaftortezacaftorivacaftor is a triple combination cystic fibrosis transmembrane regulator (CFTR) modulator that targets the defective cystic fibrosis transmembrane regulator protein in individuals with responsive CFTR variants and has transformed the lives of many people with cystic fibrosis. , Elexacaftor and tezacaftor are CFTR ...

  2. en.wikipedia.org › wiki › CFTR_(AM)CFTR (AM) - Wikipedia

    CFTR (680 AM; “680 NewsRadio Toronto”) is a commercial all-news radio station licensed to Toronto, Ontario, serving the Greater Toronto Area.

  3. Jun 6, 2020 · More recently, a new class of therapeutics called CFTR modulators, small molecule agents that potentiate CFTR or restore diminished protein levels at the cell surface, have been developed. These therapeutics directly address the functional protein defects that cause cystic fibrosis.

    • 10.1183/16000617.0068-2019
    • 2020/06/06
    • Eur Respir Rev. 2020 Jun 30; 29(156): 190068.
  4. Jul 12, 2019 · Cystic fibrosis (CF) is a life-limiting disease caused by defective or deficient cystic fibrosis transmembrane conductance regulator (CFTR) activity. The recent advent of the FDA-approved CFTR...

    • Elena K Schneider-Futschik
    • elena.schneider@unimelb.edu.au
    • 2019
  5. Here, we present the current understanding of CFTR mutations, protein function, and disease pathophysiology, consider strengths and limitations of current management strategies, and look to the future of multidisciplinary care for those with cystic fibrosis.

  6. CFTR is a radio station from Toronto, Ontario, airs at 680 AM, branded as CityNews 680. That radio plays all-news format, also publishes current gas prices and traffic reports. The former name of CFTR is 680 News and in June 2021 it was rebranded to the CityNews.

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  8. Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. Geneticist Lap-Chee Tsui and his team identified the CFTR gene in 1989 as the gene linked with CF (cystic fibrosis).

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