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  1. Radiation therapy provides a useful adjunct to surgery by ensuring optimal local control in patients with node positivity. For patients undergoing breast-conserving surgery, radiation therapy has been shown to reduce locoregional recurrence and is therefore part of the current standard of care.

  2. A combination of local and systemic treatment including surgery, radiation therapy, chemotherapy, targeted therapy (eg, human epidermal growth factor receptor 2 [HER2] inhibitors), and endocrine therapy are used to synergistically treat and eradicate breast cancer.

    • Hannah L. Chung, Huong T. Le-Petross, Jessica W. T. Leung
    • 2021
  3. Mar 3, 2020 · Patients with cIMN+ breast cancer achieved favorable outcomes after the combined treatment of breast surgery, IMN-targeted RT, and systemic therapy. In patients with IMN size ≥1.0 cm, a high IMN radiation dose was significantly associated with improved DFS.

    • Kyungmi Yang, Haeyoung Kim, Doo Ho Choi, Won Park, Jae Myoung Noh, Won Kyung Cho
    • 10.1186/s13014-020-1464-0
    • 2020
    • Radiat Oncol. 2020; 15: 16.
  4. Apr 9, 2020 · Modern radiotherapy techniques, such as deep inspiration breath hold, should be cautiously employed in patients treated according to the inclusion criteria of the Z0011 as it will result in a lower dose to the axillary levels. Keywords: Breast cancer, Lymphatics, Radiotherapy, Regional nodal irradiation. Go to: Introduction.

    • Marciana Nona Duma
    • 10.1159/000507040
    • 2020
    • 2020/04
    • SA-CME LEARNING OBJECTIVES
    • Introduction
    • TEACHING POINTS

    After completing this journal-based SA-CME activity, participants will be able to: Identify the suspicious features that are suggestive of lymph node metastases. Discuss the anatomic location of lymph node metastases and corresponding nodal stage. Describe the rationale for performing sentinel lymph node biopsy and TAD. See rsna.org/learning-center...

    The extent of lymph node metastases is a key determinant of patient outcome and survival in breast cancer. Traditionally, surgery was the reference standard for providing the lymph node staging informa-tion. As the use of neoadjuvant systemic therapy (NST) has in-creased and surgical management has evolved toward less extensive surgery when possibl...

    As the use of NST has increased and surgical management has evolved toward less extensive surgery when possible, radio-logic staging has become more important. The imperceptible cortex seen in a benign type I node or the thin 3-mm or less cortex of a type II node is replaced by a variable appearance of diffuse but symmetric cortical thick-ening see...

  5. Mar 30, 2020 · Radiation therapy of patients with breast cancer remains a challenging and rapidly changing treatment. Regional lymph node irradiation in younger trials appears to deliver superior target coverage as well as a reduction in long-term toxicity subsequent leading to a small benefit in the overall survival rate.

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  7. Nov 3, 2023 · Postoperative radiation therapy has been a mainstay of treatment for early breast cancer for many years. The efficacy of chest wall radiation therapy after mastectomy and whole breast irradiation after breast conserving surgery was established through randomised controlled trials.

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