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  1. Treatment enables people to counteract addiction's disruptive effects on their brain and behavior and regain control of their lives. The Journal of Neuroscience, 21 (23):9414-9418. 2001. These images showing the density of dopamine transporters in the brain illustrate the brain's remarkable ability to recover, at least in part, after a long ...

  2. Jul 29, 2024 · NIDA-supported research has led to the development of effective interventions for treating substance use disorders and overdose, including medications (such as those for opioid use disorder or tobacco dependence), behavioral interventions, and digital therapeutics. NIDA continues to support and conduct research to develop and implement safe ...

  3. For example, the Matrix Model—a 16-week comprehensive behavioral treatment approach that combines behavioral therapy, family education, individual counseling, 12-step support, drug testing, and encouragement for non-drug-related activities—has been shown to be effective in reducing methamphetamine misuse. 33,34 Contingency management interventions, which provide tangible incentives in ...

  4. Oct 17, 2023 · NIDA is advancing the science on emergency medications like naloxone, which can save a life during an opioid overdose. Overdose reversal medications are safe and effective life-saving tools that can be given to someone experiencing a drug overdose. As a harm reduction tool, overdose reversal medications play a critical role in a science-based approach to the drug overdose crisis.

  5. A variety of effective treatments are available for heroin use disorder, including both behavioral and pharmacological (medications). Both approaches help to restore a degree of normalcy to brain function and behavior, resulting in increased employment rates and lower risk of HIV and other diseases and criminal behavior. Although behavioral and pharmacologic treatments can be extremely useful ...

  6. There are effective treatments that support tobacco cessation, including both behavioral therapies and FDA-approved medications. FDA-approved pharmacotherapies include various forms of nicotine replacement therapy as well as bupropion and varenicline. Research indicates that smokers who receive a combination of behavioral treatment and ...

  7. Sep 25, 2024 · Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to an analysis funded by the National ...

  8. Jan 24, 2024 · Psilocybin is a chemical in certain types of mushrooms that grow on nearly every continent. The mushrooms have a long history of use in traditional ceremonies. Some people use them recreationally or to try to improve their mental health, although researchers still have much to learn about psilocybin’s potential uses as a medicine.

  9. In treatment, the drug abuser is taught to break old patterns of thinking and behaving and to learn new skills for avoiding drug use and criminal behavior. Individuals with severe drug problems and co-occurring disorders typically need longer treatment (e.g., a minimum of 3 months) and more comprehensive services.

  10. Jul 15, 2024 · In an ideal world, treatment and prevention systems in the U.S. would proactively address social drivers of health and mental health needs to stop the cycle between addiction and incarceration. Moving away from criminalization of substance use disorders toward a public-health approach would remove a key structural practice that perpetuates inequalities.

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