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  1. May 28, 2019 · Banned in the U.S. since the early 1970s, synthetic estrogens such as DDT and PCBs continue to poison the environment, partially due to their ongoing use in developing countries and their ability to vaporize and drift across the globe.7.

  2. May 1, 1997 · Although there are many substances considered to be environmental estrogens, including pesticides, pollutants, and various chemicals, this paper deals with the estrogenicity of BPA, and I will therefore focus my discussion primarily on the estrogenic substances derived from plastics.

    • David Feldman
    • 1997
  3. John A. McLachlan holds professorships in phar-macology at Tulane and Xavier Universities. He is also adjunct professor of environmental health sciences at Tulane and director of the Tulane/Xavier Center for Bioenvironmental Research. He has been studying the mechanism of action ofestro-genic chemicals for over 20 years, having coined the ...

  4. Feb 4, 2021 · Bisphenol A, dichlorodiphenyltrichloroethane, dichlorodiphenyldichloroethylene, polychlorinated biphenyls and phthalates are major toxicants that interfere with the normal estrogen/androgen pathways leading to infertility in both sexes through many ways, including DNA damage in spermatozoids, altered methylation pattern, histone modifications an...

    • Saira Amir, Syed Tahir Abbas Shah, Charalampos Mamoulakis, Anca Oana Docea, Olga-Ioanna Kalantzi, At...
    • 10.3390/ijerph18041464
    • 2021
    • 2021/02
  5. Feb 26, 2024 · “A well-established body of scientific research indicates that endocrine-disrupting chemicals that are part of our daily lives are making us more susceptible to reproductive disorders, cancer, diabetes, obesity, heart disease, and other serious health conditions,” said the report’s lead author, Andrea C. Gore, PhD, of the University of Texas at Austin.

  6. Jun 6, 2019 · The importance of estrogens in breast cancer progression is highlighted by the fact that approximately 70% of all breast tumors express the estrogen receptor and proliferate in the presence of estrogenic hormones ( Dowsett et al., 2010 ). There has been increasing interest and debate as to whether environmental exposure to endocrine disrupting ...

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  8. Aug 8, 2023 · The societal burden posed by EDCs is substantial, with attributable disease costs of US$ 340 billion per year in the USA (2.3% of GDP), € 163 billion per year in the European Union (EU) and CAD ...

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