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May 1, 2012 · Chemically-synthetized environmental estrogens can be found in plastics, detergents, surfactants, pesticides and industrial chemicals. In addition, a new class of environmental estrogens – the metalloestrogens – has been identified.
- Cecilia Chighizola, Pier Luigi Meroni
- 2012
Environmental estrogens can be of natural origin, being isolated from plants (phytoestrogens) and fungal products from Fusarium sp (mycoestrogens). Moreover, a number of synthetic chemicals have estrogen-like activity, referred to as xenoestrogens. Chemically-synthetized environmental estrogens can be found in plastics, deter-
Jan 1, 2022 · The detection of synthetic estrogens and estrogenic chemicals in the environment has increased significantly across the globe since the 1940s. The environmental fate of these chemicals is vast and depends largely on the unique physicochemical properties of each chemical.
- 10.1016/j.mce.2021.111415
- 2022/01/01
An efficient three-step synthesis of the heterocyclic core and structure-guided optimization of the substituents resulted in a series of potent nonsteroidal estrogens. The chemical tractability of the thieno[2,3-d]pyrimidine chemotype will support the design of new estrogen receptor ligands as therapeutic hormones and antihormones.
Jan 1, 2022 · The detection of synthetic estrogens and estrogenic chemicals in the environment has increased significantly across the globe since the 1940s. The environmental fate of these chemicals is vast and depends largely on the unique physicochemical properties of each chemical.
- L. Varticovski, D.A. Stavreva, A. McGowan, R. Raziuddin, G.L. Hager
- 2022
Mar 1, 2006 · Xeno-oestrogens form a diverse group of man-made chemicals which have been released into the environment from agricultural spraying (herbicides, pesticides), as by-products of industrial processes and waste disposal (polychlorinated biphenyls (PCBs), dioxins), or as discharges from treatment systems (alkyl phenols).
People also ask
Are environmental estrogens chemically synthetized?
Do endogenous sex hormones affect the response to environmental chemicals?
What are industrial estrogens?
How do environmental estrogens affect pharmacological effects?
Environmental estrogens are chemically synthetized compounds, e.g. organochlorides (polychlorinated biphenyls (PCBs), dichloro-diphenyltrichloroethane (DDT)), etc. The effects of environmental estrogens or xenoestro-gens are determined by the receptors with which they interact, by the tissue distribution of these
