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Nov 2, 2020 · Remote ischaemic conditioning (RIC) is currently being explored as a non-invasive method to attenuate ischaemia/reperfusion injuries in organs. A randomised clinical study (CONTEXT) evaluated the effects of RIC compared to non-RIC controls in human kidney transplants. Methods.
May 3, 2024 · Remote ischemic conditioning (RIC) has the potential to benefit graft function following kidney transplantation by reducing ischemia-reperfusion injury; however, the current clinical evidence is inconclusive.
- 10.1186/s12871-024-02549-y
- 2024
- BMC Anesthesiol. 2024; 24: 168.
Experimental and clinical studies have shown protection by remote ischemic conditioning (RIC). We hypothesized that recipient RIC before kidney graft reperfusion reduces the time to graft recovery.
Sep 29, 2021 · We used samples from the CONTEXT trial cohort that examined the effects of four cycles of RIC during kidney transplant surgery on kidney graft function. We aimed to evaluate if RIC affected the frequency of circulating myeloid (m)DCs and pDCs and the distinct subset of ILT3 + DCs as well as the expression of activation markers human leucocyte ...
- Marie B Nielsen, Marie B Nielsen, Kristian Ravlo, Kristian Ravlo, Marco Eijken, Nicoline V Krogstrup...
- 10.1111/cei.13658
- 2021
- Clin Exp Immunol. 2021 Nov; 206(2): 226-236.
Nov 2, 2020 · A randomised clinical study (CONTEXT) evaluated the effects of RIC compared to non-RIC controls in human kidney transplants. Methods: RIC was induced prior to kidney reperfusion by episodes of obstruction to arterial flow in the leg opposite the transplant using a tourniquet (4 × 5 min).
- Adam M. Thorne, Honglei Huang, Darragh P. O‘Brien, Marco Eijken, Marco Eijken, Nicoline Valentina Kr...
- 2020
This brief commentary aims to discuss the effects of RIC on clinical outcomes and proinflammatory cytokines in patients undergoing kidney transplantation.
Dec 1, 2020 · Using a porcine kidney transplant model, we aimed to decipher the subclinical molecular effects of a RIC regime, compared to non-RIC controls.
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