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Among adverse events that affect the tolerability of antidepressants in youth is activation, a cluster of symptoms that represent a hyperarousal event characterized by impulsivity, restlessness, and/or insomnia.
- Symptoms and Signs
- Time of Onset After Ssri Administration
- Relationship to Drug Dose
- Biological Susceptibility
The psychiatric signs and symptoms include irritability, agitation, somatic manifestations of anxiety, panic attacks, restlessness, hostility, aggression, insomnia, disinhibition, emotional liability, impulsivity, social withdrawal, akathisia (psychomotor restlessness), odd behavior, hypomania/mania, and paranoia or other psychotic symptoms [1, 16,...
Although it has been reported that activation can occur at any time during the course of treatment, there seems to be a tendency for it to appear during the first 2 or 3 weeks after drug initiation [1, 18]. These findings have been tied to studies of suicidal risk in relation to SSRI treatment, although this remains controversial [2, 16]. This issu...
Some studies found no relationship between the SSRI dose and the appearance of activation syndrome , whereas others reported that children treated with a lower dose of SSRI are more prone to behavioral activation . However, most studies suggest that higher doses are associated with higher rates of activation [7, 14]. Conversely, it is possible that...
Activation is more common in children and adolescents than adults and up to twice as common in children than adolescents . A recent naturalistic study reported that patients who suffered from such adverse events were significantly younger than those who did not (p = 0.02), and every 1-year increase in age was associated with a 27 % decrease in the ...
- Maya Amitai, Alon Chen, Alon Chen, Abraham Weizman, Alan Apter
- 2015
Feb 1, 2018 · Among adverse events that affect the tolerability of antidepressants in youth is activation, a cluster of symptoms that represent a hyperarousal event characterized by impulsivity, restlessness, and/or insomnia.
- Marissa J. Luft, Martine Lamy, Melissa P. DelBello, Robert K. McNamara, Jeffrey R. Strawn, Jeffrey R...
- 2018
Dec 22, 2018 · The widely held belief that emotional and psychological processes affect our physical health, mental health and general well-being are central to a holistic view of the individual, and as such, it is a useful foundational concept in integrative medicine.
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- Complaint/Disorder
Jan 18, 2023 · Given the overlap of potential adverse effects of pharmacotherapy and physical and somatic symptoms of depression or anxiety, 21 - 23 which are associated with patient age, family characteristics, and endogenous factors, it is critical to assess symptoms before beginning treatment.
- 2
- 43, Issue7
- 18 January 2023
Sep 5, 2023 · Repression is the unconscious blocking of distressing thoughts, impulses, feelings, or memories out of your conscious mind. In psychology, repression is seen as a defense mechanism that helps protect against anxiety arising from thoughts or emotions that are too painful to acknowledge.
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Nov 8, 2024 · Repression Symptoms. Repression is a type of emotional regulation. While protective in nature, repression also has several negative consequences that can affect you physically, emotionally, and...
