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eration. Hypoxic tumor cells are relatively insensitive to conventional therapy owing to cellular adaptations effected by the hypoxic microenvironment. Recent efforts have aimed to alter the hypoxic state and to reverse these adaptations to improve treatment outcome. One way to increase tumor oxygen tensions is by hyperbaric oxygen (HBO) therapy.
Apr 8, 2023 · Absolute Contraindications. There is currently only one absolute contraindication to hyperbaric oxygen therapy (HBOT): untreated pneumothorax. Placing a patient in a chamber and changing the pressure around them can result in a tension pneumothorax occurring on the ascent, which could quickly become life-threatening.
- Rohin Gawdi, Jeffrey S. Cooper
- 2023/04/08
Jun 8, 2021 · Tumor cells have long been recognized as a relative contraindication to hyperbaric oxygen treatment (HBOT) since HBOT might enhance progressive cancer growth. However, in an oxygen deficit condition, tumor cells are more progressive and can be metastatic. HBOT increasing in oxygen partial pressure may benefit tumor suppression.
- Shao-Yuan Chen, Koichi Tsuneyama, Mao-Hsiung Yen, Jiunn-Tay Lee, Jiun-Liang Chen, Shih-Ming Huang
- 2021
Jun 26, 2018 · Cancer cells' relationship with oxygen is a bit more complicated, and that realization has led to decades of research into whether oxygen is good for cancer or bad for it. The answers are still not definitive, but some have used the unknowns to fuel unsupported claims that certain types of oxygen therapies, including hyperbaric oxygen (HBO) therapy, can cure cancer.
Jun 8, 2021 · Tumor cells have long been recognized as a relative contraindication to hyperbaric oxygen treatment (HBOT) since HBOT might enhance progressive cancer growth. However, in an oxygen deficit ...
- Shao-Yuan Chen, Koichi Tsuneyama, Mao-Hsiung Yen, Jiunn-Tay Lee, Jiun-Liang Chen, Shih-Ming Huang
- 2021
tumor-inhibitory effects in certain cancer subtypes, and we thus strongly believe that we need to expand our knowledge on the effect and the mechanisms behind tumor oxygenation. Keywords Hyperbaricoxygentherapy .Cancer .Hypoxia Search terms Pubmed was searched for articles concerning hyperbaric oxygen (HBO) and cancer for the period from 2004 to
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When tumor cells adapt to the imbalance between oxygen supply and demand, malignant features of solid tumors such as resistance to cell death, angiogenesis, and metastasis were invariably enhanced. 6,7 Emerging features of cancer development such as genome instability, the enrichment of cancer stem cells, and aberrant exosomal secretion were also suggested as hallmarks of tumor hypoxia. 8–10 ...