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  1. Studies suggest that a low-carb diet may cause depression and anxiety ⁠— if it's deficient in healthy complex carbs like fruits, vegetables and whole grains. The food you eat affects your mental health as well as your physical health.

    • Improve blood glucose control. The higher your blood sugar, the higher your brain sugar . . . so every time your blood sugar spikes to unhealthy highs, you’re flooding your brain tissue with excess glucose.
    • Lower blood insulin levels. Persistently or repeatedly high insulin levels can cause the insulin receptors on the surface of the blood-brain barrier to become insulin-resistant, meaning they can become damaged, desensitized, and dwindle in number.
    • Reduce inflammation. High-sugar diets promote excessive, unnecessary inflammation inside the brain, triggering the release of various inflammatory cytokines—tiny SOS signals that recruit first-responder cells to the scene.
    • Boost antioxidant defenses. High-sugar diets cause excessive, unnecessary oxidative damage. Flooding cells with too much glucose all at once leads to a spilling over of oxygen free radicals, which are normally mopped up by our own natural, internal antioxidant molecules (such as glutathione).
  2. Mar 15, 2023 · Although our analysis on eight studies indicated no significant effect of the low carbohydrate diet on depression and anxiety, the results of the subgroup analysis indicated that the low carbohydrate diet increase anxiety in the Australia region, and in studies with <26 % carbohydrate intake.

  3. Philip Cowen, chief of psychiatry at Oxford University in the U.K., reported in a study published in the British Journal of Psychiatry that the mood problem with low-carb diets was measurable...

  4. Mar 15, 2023 · No significant association has been shown between a low carb ketogenic diet and the risk of depression and anxiety. Well-designed clinical trials are needed to prove the efficacy of KD before considering it in the clinical care of patients.

  5. Mar 15, 2023 · The present study did not demonstrate significant association between a low carbohydrate diet and improvement of depression and anxiety. More accurate studies are needed to reach definitive conclusions.

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  7. Symptoms of anxiety, depression and dysperception improved with ketogenic and ‘optimal carbohydrate level’ diets in 82% of participants. 60% of participants reported transient adverse effects, including fatigue, nausea, weakness, headache and palpitations; improved after administration of potassium salts. Case reports.

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