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- Technically, no. Ozempic was FDA-approved for the treatment of Type 2 diabetes in 2017, while Wegovy was specifically approved for the treatment of obesity and weight loss in 2021. Wegovy and Ozempic both contain the same active ingredient: semaglutide. Some doctors may prescribe Ozempic off-label for weight management.
health.usnews.com/wellness/articles/is-ozempic-safe-and-effective-for-weight-lossOzempic for Weight Loss: Side Effects and Safety - US News Health
People also ask
Can Ozempic help you lose weight?
How effective is wegovy vs Ozempic for weight loss?
Is Ozempic the same as wegovy?
How long does it take to lose weight from Ozempic?
Should people with diabetes use wegovy or Ozempic?
Is wegovy a good weight loss drug?
Long-term use can lead to sustained weight loss and improvements in overall metabolic health. However, you need to use semaglutide in conjunction with a healthy eating and exercise program to achieve lasting results.
- Mayo Clinic Diet
- Overview
- What is Ozempic?
- Is Ozempic FDA approved for weight loss?
- What’s the difference between Ozempic and Wegovy?
- Does Ozempic help with weight loss?
- How long does it take to lose weight on semaglutide?
- Is Ozempic safe?
- Can you regain weight after using semaglutide?
- Can someone take semaglutide long-term?
- What are other treatments for obesity?
Health experts provide clear answers to nine of the most frequently asked questions about using Ozempic (semaglutide) to aid with weight loss.
•Experts say that glucagon-like peptide 1 (GLP-1) drugs like Ozempic, known generically as semaglutide, can help people with obesity lose weight.
•Ozempic is not FDA-approved for weight loss. Another brand, Wegovy, also semaglutide, is.
•Experts share that people who are not diabetic or obese should not use Wegovy or Ozempic for any reason, including to lose small amounts of weight.
The glucagon-like peptide 1 (GLP-1) drug Ozempic received FDA approval for use in adults with type 2 diabetes in late 2017. But lately, it’s been in the headlines for other reasons: Purported weight loss benefits and a shortage.
“People are talking about them because there is a trend of celebrities and influencers increasingly turning to off-label use of GLP-1 medications like Ozempic for weight loss by people who are not obese or diabetic,” says Dr. Rekha Kumar, a New York City-based endocrinologist and head of medical affairs at the weight care program Found.
Ozempic is a brand name for the drug known as semaglutide, explains Dr. Angela Fitch, FACP, FOMA, the president of the Obesity Medicine Association and chief medical officer of knownwell, a weight-inclusive healthcare company.
Kumar notes that Ozempic is a weekly injectable medication for people with type 2 diabetes. Its initial FDA approval was for doses of 0.5 mg or 1 mg. In 2022, the FDA approved a higher dose of 2 mg.
No.
“Ozempic is only approved for diabetes,” says Dr. Charlie Seltzer, a Philadephia-based physician with board certifications in obesity and internal medicine.
But that’s where some of the confusion comes in.
“The active ingredient, semaglutide, is approved for weight loss under the trade name Wegovy,” Seltzer says.
Both Ozempic and Wegovy are brand names for semaglutide and injectables. But they’re not exactly the same.
“Wegovy is FDA-approved for the treatment of overweight and obesity,” Kumar says. “Wegovy contains a higher dose of semaglutide, [2.4 mg], than Ozempic and was developed specifically for the treatment of overweight and obesity.”
Kumar notes that the research around semaglutide and weight loss used Wegovy’s dosing, including one from 2021 that indicated that once-weekly doses of 2.4 mg of semaglutide could reduce body weight when combined with lifestyle changes.
“[In the] study, those who took the medication and made lifestyle changes lost almost 15% of their body weight, on average, compared to 3% in the placebo group,” Kumar says.
So, yes, semaglutide — at least at a higher 2.4 mg dose —may help with weight loss. Though it’s unclear if the 0.4 mg difference in dosing for Ozempic versus Wegovy matters, Seltzer notes the two work the same way.
“Ozempic causes…appetite suppression and increases the time it takes food to exit the stomach, leading to feeling full longer,” Seltzer says. “It does nothing magical to metabolism.”
And Kumar notes that, despite what some celebrities and social media influencers may claim, these drugs are not meant for people looking to lose a couple of pounds.
“Normal-weight patients without diabetes might lose weight if they take GLP-1s, but the risks of the medication outweigh the benefit of weight loss just to be thin versus treating a disease,” Kumar says. “GLP-1s have not been studied in this population, and we will likely see more side effects with this type of inappropriate use.”
Experts share that the answer to this question will vary from person to person.
“Generally, it takes a few weeks to start seeing the effects of weight loss from Ozempic,” says Kumar.
Part of this is that people do not begin taking all 2.4 mg of Wegovy at once. Instead, they start at a dose of 0.25 mg per week and increase every four weeks, maxing out at 2.4 mg.
“The dose is gradually raised every four weeks to lessen the likelihood of side effects,” says Seltzer. “Once the dose that causes appetite suppression sufficient to cause a calorie deficit is achieved, weight loss happens quickly.”
Ozempic is generally considered safe in doses up to 2 mg. for adults with type 2 diabetes, but experts share that some people should not take it.
“It should be avoided in many populations, including but not limited to people with a history of pancreatitis, people who have had medullary thyroid cancer or who are at increased risk for medullary thyroid cancer,” Seltzer says.
Your doctor can help you determine if you are a good candidate for Ozempic. Additionally, some people may experience side effects. Fitch says common ones include:
•nausea
•constipation
•dizziness
A trial of nearly 2,000 people published in 2022 indicated that people who stopped taking 2.4 mg doses of semaglutide had regained two-thirds of the weight they had lost one year after cessation.
“Once the drug is stopped or loses its effectiveness, the same issues that got the people into trouble in the first place will still be there, and the weight will come right back on,” Seltzer says.
Fitch agrees,
“Whatever you do as a person to help with weight loss, you have to keep doing, or the weight will come back,” Fitch says. “This is the way the human body is engineered. It is built to protect its weight at all costs.”
Long-term care is essential.
“Since obesity is a chronic disease, you must treat it chronically, ongoing in a coordinated comprehensive way,” Fitch says. “Patients must work with their doctor for a holistic approach to metabolic health, weight management, and primary care.”
Kumar says semaglutide is safe for long-term use, and Fitch says continuing to take it may help a person maintain weight loss.
“You have to continue the medication you take if it has helped you to lose weight, just like you continue cholesterol medication once your cholesterol is lower. If you stop it, your cholesterol goes back up,” Fitch says.
First, Fitch notes that any treatment for obesity should be non-judgmental and lean into shared decision-making.
“Obesity is a lifelong chronic disease for most people and should be treated in a compassionate and comprehensive patient-centered way, such as shared decision making around taking medication or having surgery with the risks and benefits in mind,” Fitch says.
Lifestyle tweaks like diet and exercise are often recommended as first-line treatments, but they do not work for everyone.
“Obesity is a complex disease with many factors,” Fitch says. “When lifestyle changes are not enough…we add in other treatments to help patients live longer, healthier, better quality lives.”
- Beth Ann Mayer
Oct 3, 2023 · A new real-world study has found that the drug semaglutide (better known by the brand names Ozempic and Wegovy) effectively helped people with type 2 diabetes lose weight and improve blood sugar...
- Mayo Clinic Diet
- Eat a healthy diet. Wegovy helps to reduce appetite and calorie intake. For best results, you should take Wegovy while following a low-calorie diet. Aim for at least 1,200 calories per day and choose foods that are nutrient dense and easy to consume.
- Embrace a physically active lifestyle. Exercise is foundational in any weight-loss program, but particularly important while taking weight-loss medications for two key reasons.
- Prioritize sleep and stress management. Sleep and stress also play significant roles in weight management. Inadequate or poor-quality sleep can disrupt the body’s ability to regulate appetite.
- Tailor your dose of Wegovy. Like with other medications, individual responses to weight-loss medications vary. When starting Wegovy, you are likely to start on a lower dose and gradually increase the dose up to a maximum of 2.4 mg weekly.
Jul 10, 2024 · Ozempic and its sister medication Wegovy are highly effective solutions for weight loss in individuals who are living with obesity or overweight.
Apr 3, 2024 · Because Ozempic and Wegovy both contain the drug semaglutide, Ozempic may also help with weight loss, but this use would be considered off-label. Ozempic is primarily meant to treat high blood sugar levels associated with type 2 diabetes .
Sep 8, 2023 · Weight loss medications like Ozempic and Wegovy can help people drop pounds quickly, but they can also cause a rapid loss of muscle mass and bone… READ MORE
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futurhealth.com has been visited by 100K+ users in the past month
Take our quiz, Get preapprove for Ozempic and personalized weight loss program. 2 Min Quiz To Know Body Type and get Ozempic prescription
With Alan Meds, pay only for the medication you need. Fast, overnight Semaglutide delivery. Alan Meds brings you Semaglutide with everything included. Convenience meets quality care.
