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      • They strongly suggest that pharmacologic agents are most effective when used with adjunctive psychosocial therapy. Very few studies have combined pharmacological and psychological interventions in treating anger.
      jaapl.org/content/jaapl/37/4/473.full.pdf
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  2. Glancy and Knott 26 found several pharmacological agents to be efficacious in managing maladaptive anger. Careful assessment of the patient to detect underlying major psychiatric conditions is the first necessity, as these conditions may impede positive gains from psychological treatment alone.

  3. Dec 1, 2015 · A rational algorithm for effective pharmacotherapy for impulsive aggression takes into account five factors: sufficiently defined and characterized aggressive behavior; availability of agents studied by trials of sufficient quality; risks, side effects, and contraindications; severity of aggressive outbursts; and co-occurring mental and medical ...

  4. This meta-analysis supports the potential integra-tion of psychological and pharmacological treat-ments of maladaptive anger. Glancy and Knott24–26 completed a three-part series on the use of pharma-cology to treat anger and aggression.

  5. Oct 7, 2019 · If psychosocial interventions are not sufficient to reduce IA, adjunctive pharmacological treatment is recommended . As summarized above, the currently recommended strategy is to treat the primary disorder first (using monotherapy when possible), in conjunction with continuing psychosocial interventions (Khan et al. 2019). Psychopharmacological ...

    • Daniel F. Connor, Jeffrey H. Newcorn, Keith E. Saylor, Birgit H. Amann, Lawrence Scahill, Adelaide S...
    • 2019
  6. Feb 14, 2019 · Here we will propose the establishment of a class of anti-maladaptive aggression agents to begin addressing this clinical issue. The development of such a class would unify the various drugs currently used to treat maladaptive aggression and streamline the treatment approach towards IA.

    • Adelaide S. Robb, Stefan Schwabe, Gianpiera Ceresoli-Borroni, Azmi Nasser, Chungping Yu, Ronald Marc...
    • 2019
  7. May 5, 2020 · Antipsychotic medications and anticonvulsant mood stabilizers are used as pharmacotherapeutic treatments for maladaptive aggression in a variety of adolescent psychiatric settings [ 11 - 16 ].

  8. Among first-line atypicals (risperidone (Risperdal), olanzapine (Zyprexa), quetiapine (Seroquel), ziprasidone (Geodon), and aripiprazole (Abilify), risperidone is the most extensively studied medication for the treatment of aggression and CD in youth.

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