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- Psychosocial interventions may be effective alone or in combination with pharmacological treatments. Psychotropic agents (e.g., stimulants, mood stabilizers, β-blockers) have also been shown to have limited efficacy in reducing aggression.
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Can psychotropic agents be used to treat impulsive aggression?
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Are mood stabilisers effective in the treatment of impulsive aggression?
Evidence suggests that anti-impulsive aggression agents (AIAAs) can diminish or prevent impulsive aggression even when occurring with personality pathology such as borderline or antisocial personality disorder (ASPD), common conditions in offender populations.
- Pharmacologic treatment of impulsive aggression with ...
Strong evidence for efficacy in impulsive aggression exists...
- Pharmacologic treatment of impulsive aggression with ...
Dec 1, 2015 · A rational algorithm for effective pharmacotherapy for impulsive aggression takes into account five factors: sufficiently defined and characterized aggressive behavior; availability of agents studied by trials of sufficient quality; risks, side effects, and contraindications; severity of aggressive outbursts; and co-occurring mental and medical ...
The present study assessed the quality of pharmacotherapy trials to treat impulsive aggressive behavior. While a search of the literature found 55 peer-reviewed published studies on the pharmacotherapy of aggression, only 23 met criteria for inclusion in the quality analysis.
- Alan R. Felthous, Sarah L. Lake, Brian K. Rundle, Matthew S. Stanford
- 2013
Strong evidence for efficacy in impulsive aggression exists from randomized controlled trials for most of the common AEDs (phenytoin, carbamazepine, oxcarbazepine, lamotrigine, valproate/divalproex sodium, topiramate). Additional controlled studies are needed for tiagabine and gabapentin.
- Matthew S. Stanford, Nathaniel E. Anderson, Sarah L. Lake, Robyn M. Baldridge
- 2009
- Co-occurring Conditions
- Psychopharmacotherapy History
- Affordability and Availability
- Discussion
- Conclusions
Mental Disorders Treatment of the principal disorder can reduce aggressive behavior that is secondary to the condi-tion. Sometimes the very medicine used to treat the principal disorder happens to be an effective AIAA: a mood stabilizer for bipolar disorder, for example. In that case, the AIAA is FDA approved for the princi-pal disorder and control...
Obtaining the patient’s psychopharmacotherapy history is an important step in psychiatry generally. For impulsive aggression secondary to another disor-der (not the topic of this algorithm), the importance is obvious. If a bipolar patient’s impulsive aggression secondary to mania was effectively controlled in the past with lithium, for example, thi...
Not often mentioned in scientific articles is the reality that a medicine must be available and afford-able to the patient. Medicine has no effect if it is not taken. If the prescribed medicine is unavailable or unaffordable, it cannot be prescribed. The AIAA may be on the hospital formulary and easily administered while the patient is in the hospi...
The treatment of and pharmacotherapy for IED are addressed in one of psychiatry’s major text books.76 The present, more expansive algorithm for the selection of AIAAs in clinical practice places two considerations at the forefront: identification of effi-cacious AIAAs based on drug trials of sufficient qual-ity and proper characterization of the ag...
Research supports the use of certain AIAAs in the treatment of impulsive aggression that has been ade-quately defined and diagnosed, even if no AIAA is FDA approved for this indication. Research reports alone, however, do not inform the clinician as to which AIAA would be the best selection for a partic-ular patient with primary impulsive aggressio...
Mood stabilisers are often used off-license for the treatment of aggression associated with a variety of psychiatric conditions, but their efficacy in these and in idiopathic aggression is not known. Aims.
The treatment of pediatric aggression often involves psychotropic agents. Despite growing research on pediatric psychopharmacology, however, clinical issues regarding medication management of persistent behavioral problems remain poorly addressed.
