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An adverse reaction is an undesirable side effect that occurs after a vaccination. Vaccine adverse reactions are classified as 1) local, 2) systemic, or 3) allergic (additional information). Local reactions (e.g., redness) are usually the least severe and most frequent.
The goal of adverse event investigation and reporting is to determine whether these events are associated with the vaccine or immunization. Vaccine attributable risk is defined as the difference between the frequency of the event in the vaccinated compared to the unvaccinated population.
When adverse reactions do occur, they can range from minor (e.g., soreness, itching) to serious (e.g., anaphylaxis). Be prepared. Vaccinators should know how to recognize allergic reactions, including anaphylaxis. Have a plan and supplies ready to provide appropriate medical care if an event occurs. Medical Management of Vaccine Reactions in Adults
Psychological fright and syncope (fainting) All vaccines have the potential to cause an adverse reaction. In order to minimize adverse reactions, patients should be carefully screened for precautions and contraindications before vaccine is administered. Even with careful screening, reactions may occur.
Serum sickness–like reactions (SSLR) have been reported with hepatitis B, 60 influenza, 61-63 pneumococcal, 64 rabies, 65 and tetanus 66 vaccines. The diagnosis of SSLR is generally based on history with typical manifestations of rash and arthralgia.
- Anne Des Roches, François Graham, François Graham, Philippe Begin, Philippe Begin, Louis Paradis, Lo...
- 2021
Jul 31, 2024 · Vomiting, muscle aches, fever, sore throat, and cough are other possible side effects. If these problems occur, they usually begin soon after vaccination and are mild and short-lived. As with any medicine, there is a very remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death.
Though uncommon, potential serious adverse events following immunization (AEFI) can also occur. The following resources help to support providers in providing relevant information to those receiving vaccines, as well as when and how to report AEFIs.
