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When adverse reactions do occur, they can range from minor (e.g., soreness, itching) to serious (e.g., anaphylaxis). Be prepared. Vaccinators should know how to recognize allergic reactions, including anaphylaxis. Have a plan and supplies ready to provide appropriate medical care if an event occurs. Medical Management of Vaccine Reactions in Adults
- Updates
- Benefit and Risk Communication
- Preventing Adverse Reactions
- Managing Acute Vaccine Reactions
- Reporting Adverse Events After Vaccination
- National Vaccine Injury Compensation Program
- References
Major changes to the best practice guidance include 1) more descriptive characterization of anaphylactic allergy and 2) incorporation of protocols for managing adverse reactions.
Parents, guardians, legal representatives, and adolescent and adult patients should be informed about the benefits of and risks from vaccines in language that is culturally sensitive and at an appropriate educational level. Opportunity for questions should be provided before each vaccination. Discussion of the benefits of and risks from vaccination...
Vaccines are intended to produce active immunity to specific antigens. An adverse reaction is an undesirable side effect that occurs after a vaccination. Vaccine adverse reactions are classified as 1) local, 2) systemic, or 3) allergic (additional information). Local reactions (e.g., redness) are usually the least severe and most frequent. Systemic...
Vaccine providers should be familiar with identifying immediate-type allergic reactions, including anaphylaxis, and be competent in treating these events at the time of vaccine administration. Providers should also have a plan in place to contact emergency medical services immediately in the event of a severe acute vaccine reaction. Allergic reacti...
Modern vaccines are safe and effective; however, adverse events have been reported after administration of all vaccines (3). More complete information about adverse reactions to a specific vaccineis available in the package insert for each vaccine and from CDC. An adverse event is an untoward event that occurs after a vaccination that might be caus...
The National Vaccine Injury Compensation Program, established by the National Childhood Vaccine Injury Act of 1986 (1), is a no-fault system in which persons thought to have experienced an injury or to have died as a result of administration of a covered vaccine can seek compensation. The program became operational on October 1, 1988, and is intend...
National Childhood Vaccine Injury Act, 42 U.S.C. Sect. 300aa-1 to 300aa-34 (1986).Opel DJ, Heritage J, Taylor JA, et al. The architecture of provider-parent vaccine discussions at health supervision visits. Pediatrics. 2013:2013-2037. DOI: 10.1542/peds.2013-2037CDC. Update: vaccine side effects, adverse reactions, contraindications, and precautions. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 1996;45(RR-12)...CDC. Syncope after vaccination—United States, January 2005-July 2007. MMWR Morb Mortal Wkly Rep. 2008;57(17):457-460.The goal of adverse event investigation and reporting is to determine whether these events are associated with the vaccine or immunization. Vaccine attributable risk is defined as the difference between the frequency of the event in the vaccinated compared to the unvaccinated population.
Psychological fright and syncope (fainting) All vaccines have the potential to cause an adverse reaction. In order to minimize adverse reactions, patients should be carefully screened for precautions and contraindications before vaccine is administered. Even with careful screening, reactions may occur.
Nov 11, 2020 · When adverse events following immunisation (AEFIs) do occur, it is important that they are reported, especially if they are serious, even if they are unlikely to have been caused by the vaccine itself. This ongoing surveillance is essential to ensure vaccine safety.
Though uncommon, potential serious adverse events following immunization (AEFI) can also occur. The following resources help to support providers in providing relevant information to those receiving vaccines, as well as when and how to report AEFIs.
The purpose of this review is 2-fold: first, to provide an understanding of the basic concepts that are relevant to vaccine pharmacovigilance and secondly, to provide an overview of adverse vaccine and immunization reactions, including COVID-19 vaccines.
