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AEFI general definition: any untoward medical occurrence which follows administration of an active immunizing agent and which does not necessarily have a causal relationship with the use of a vaccine. The adverse event may be any unfavourable or unintended sign, abnormal laboratory finding, symptom or disease.
An adverse reaction is an undesirable side effect that occurs after a vaccination. Vaccine adverse reactions are classified as 1) local, 2) systemic, or 3) allergic (additional information). Local reactions (e.g., redness) are usually the least severe and most frequent.
Psychological fright and syncope (fainting) All vaccines have the potential to cause an adverse reaction. In order to minimize adverse reactions, patients should be carefully screened for precautions and contraindications before vaccine is administered. Even with careful screening, reactions may occur.
Jun 25, 2024 · By reporting adverse events, possible vaccine safety concerns can be investigated, and action taken if needed. It is important to note that most people who have an adverse event following immunization can safely get immunized again.
Serum sickness–like reactions (SSLR) have been reported with hepatitis B, 60 influenza, 61-63 pneumococcal, 64 rabies, 65 and tetanus 66 vaccines. The diagnosis of SSLR is generally based on history with typical manifestations of rash and arthralgia.
- Anne Des Roches, François Graham, François Graham, Philippe Begin, Philippe Begin, Louis Paradis, Lo...
- 2021
Jul 31, 2024 · Sore arm from the injection, redness or rash where the shot is given, or fever can happen after varicella vaccination. More serious reactions happen very rarely. These can include pneumonia, infection of the brain and/or spinal cord covering, or seizures that are often associated with fever.
Nov 11, 2020 · A serious adverse event or reaction is a regulatory term, describing life-threatening events, those resulting in death, hospitalisation (or an existing hospital stay being lengthened) or persistent or significant disability/incapacity.
