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Structure elucidation refers to the process of determining the detailed arrangement of atoms within a molecule, which is often achieved through the use of techniques such as NMR and MS. AI generated definition based on: Encyclopedia of Spectroscopy and Spectrometry (Second Edition), 2010
Feb 28, 2015 · For this purpose 22 relatively simple structural tasks adopted from the textbook by M. Reichenbächer and J. Popp, “Challenges in molecular structure determination,” Springer, 2012 serve as...
Molecular Formula : The first step in structural elucidation is the determination of molecular formula and optical rotatory power. Elemental composition and hence the empirical formula is found by combustion analysis.
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The various spectroscopies are the primary method for determining the structure of compounds. If the molecule is not too large or complex, the determination should be very accurate. These are simply done and rapid. They can be combined to give overlapping information.
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One of the most widely used methods of elucidating the sequence of reactions (pathway) leading to the synthesis or degradation of a given com- pound by a given organism utilizes mutants of that organism which do not have the ability to synthesize or utilize that compound. The method is simple and elegant.
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The task of total structure elucidation is a core activity of natural products chemistry and it is important that this be completed in an unequivocal fashion. The trials and tribulations of this task are explored in Chapter 2.18 through the discussion of illustrative case examples of structure elucidations gone bad.