Search results
2 days ago · Definition. A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene. The resulting transcription produces an RNA molecule (such as mRNA).
- Repressor
Repressor proteins typically function through binding and...
- Gene Expression
If a protein activity can be measured, the gene that encodes...
- Enzyme
An enzyme is a biological catalyst and is almost always a...
- Deoxyribonucleic Acid
Deoxyribonucleic acid (abbreviated DNA) is the molecule that...
- Gene Regulation
Gene regulation. Gene regulation is one of the fundamental...
- Repressor
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA.
- CORE Promoter
- Proximal Promoter
- Distal Promoter
The core promoter region is located most proximal to the start codon and contains the RNA polymerase binding site, TATA box, and transcription start site (TSS). RNA polymerase will bind to this core promoter region stably and transcription of the template strand can initiate. The TATA box is a DNA sequence (5'-TATAAA-3') within the core promoter re...
Further upstream from the core promoter you will find the proximal promoter which contains many primary regulatory elements. The proximal promoter is found approximately 250 base pairs upstream from the TSS and it is the site where general transcription factors bind.
The final portion of the promoter region is called the distal promoter which is upstream of the proximal promoter. The distal promoter also contains transcription factor binding sites, but mostly contains regulatory elements.
promoter. Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of ...
Oct 31, 2023 · promoter: the section of DNA that controls the initiation of RNA transcription. This page titled 16.6: Eukaryotic Gene Regulation - The Promoter and the Transcription Machinery is shared under a CC BY-SA 4.0 license and was authored, remixed, and/or curated by Boundless. When transcription factors bind to the promoter region, RNA polymerase is ...
Apr 3, 2011 · By looking at every promoter in E. coli, one can generate a consensus sequence of the most common DNA bases in each position. When studying promoters, it is useful to number the DNA bases such ...
People also ask
What is a promoter in genomics?
What is a promoter in RNA polymerase?
What is the purpose of a promoter?
What is a promoter sequence?
Why are promoters important in expression vectors?
What is the function of a promoter region in a gene?
Definition. A promoter is a specific DNA sequence located upstream of a gene that serves as the binding site for RNA polymerase and other transcription factors to initiate transcription. Promoters are crucial for controlling the expression of genes, influencing when and how much a gene is expressed in both prokaryotic and eukaryotic cells.
