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a conformational change in the antibody which alters the structure of the Fc region of the molecule. Fc receptors. receptors on plasma membranes that bind to Fc region of anitbodies; many phagocytes have these. Study with Quizlet and memorize flashcards containing terms like gene rearrangement, myeloma proteins, multiple myeloma and more.
Dec 30, 2022 · (A) rearrangement of α chain and (B) β chain (C) protein structure of TCR. The enzyme that produces this diversity is a complex called the V(D)J recombinase. The recombination occurs in two parts: first double-stranded breaks are made at re- combination signal sequence (RSS) sites, then the breaks are repaired by the general double-stranded break repair mechanism.
The process of gene expression requires multiple steps depending on what the fate of the final product will be. In the case of structural and regulatory RNAs (i.e. tRNA, rRNA, snRNA, etc.) the process requires that a gene be transcribed and that any needed post-transcriptional processing take place.
Like other programmed gene rearrangements, however, gene amplification is a relatively infrequent event that occurs in highly specialized cell types; it is not a common mechanism of gene regulation. Gene amplification also occurs as an abnormal event in cancer cells, where it results in the increased expression of genes that contribute to uncontrolled cell growth.
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Sep 24, 2020 · Figure 3.10.1 3.10. 1: Pericentric inversions include the centromere, and paracentric inversions do not. A pericentric inversion can change the relative lengths of the chromosome arms; a paracentric inversion cannot. An inversion can be pericentric and include the centromere, or paracentric and occur outside of the centromere (Figure).