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Cell Rearrangement in Development and Tissue Repair. Cell rearrangement is a fundamental process in the development of multicellular organisms and in tissue repair. It involves the movement and reorganization of cells within tissues to form and reshape structures during embryonic development, as well as in the repair and regeneration of damaged ...
Key Processes in Cell Rearrangement. Several key processes contribute to cell rearrangement: Cell migration: Cells can migrate individually or collectively within tissues, guided by chemical signals and physical cues. This movement is essential for the formation of complex tissue structures and the reorganization of cells in response to injury.
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Dec 30, 2022 · (A) rearrangement of α chain and (B) β chain (C) protein structure of TCR. The enzyme that produces this diversity is a complex called the V(D)J recombinase. The recombination occurs in two parts: first double-stranded breaks are made at re- combination signal sequence (RSS) sites, then the breaks are repaired by the general double-stranded break repair mechanism.
Like other programmed gene rearrangements, however, gene amplification is a relatively infrequent event that occurs in highly specialized cell types; it is not a common mechanism of gene regulation. Gene amplification also occurs as an abnormal event in cancer cells, where it results in the increased expression of genes that contribute to uncontrolled cell growth.
- Geoffrey M Cooper
- 2000
Chromosomal Rearrangements. A chromosomal rearrangement means that pieces of chromosomes are missing, duplicated (there are extra copies), or moved around. The effects vary. They depend on which chromosome pieces are involved and how they are rearranged. Some have no effect, some are incompatible with life, and others are somewhere between.
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Jul 24, 2022 · Gene rearrangement. Gene rearrangement. a structural alteration of a chromosome that causes a change in the orderof its loci. Last updated on July 24th, 2022.
