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1,3,7-Trimethylxanthine, TMS | C8H12N4O2 | CID 427849 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
- Anne Marie Helmenstine, Ph.D.
- The molecule was first isolated by the German chemist Friedrich Ferdinand Runge in 1819.
- In plants, caffeine acts as a natural pesticide. It paralyzes and kills insects that attempt to feed on the plants. Caffeine also limits germination of seeds near the plant that could grow to compete for resources.
- When purified, caffeine is an intensely bitter white crystalline powder. It is added to colas and other soft drinks to impart a pleasing bitter note.
- Caffeine is also an addictive stimulant. In humans, it stimulates the central nervous system, heart rate, and respiration, has psychotropic (mood altering) properties, and acts as a mild diuretic.
1,3,7-Trimethylxanthine, TMS. Formula: C 8 H 12 N 4 O 2; Molecular weight: 196.2065
The most relevant naturally occurring methylxanthines are caffeine (1,3,7-trimethylxanthine), theophylline (1,3-dimethylxanthine) and theobromine (3,7-dimethylxanthine). Paraxanthine (1,7-dimethylxanthine), an isomer of theobromine and theophylline, is not produced by plants but is the major dimethylated byproduct of caffeine.
Find 1,3,7-trimethylxanthin and related products for scientific research at MilliporeSigma
Caffeine, 1,3,7-trimethylxanthine (23.3.6), is the most widely used CNS stimulant. It is an alkaloid in tea leaves ( Thea sinensis ), in coffee beans ( Coffea arabica ), in cocoa beans ( Theobroma cocao ), in cola seeds ( Cola acuminata ), and in other plants whose synthesis will be described in Chapter 23 , “Drugs for treating pulmonary ...
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Paraxanthine is a primary metabolite of caffeine formed through cytochrome P450 1A2 N-demethylation in the liver. It accounts for the majority of caffeine metabolism in humans and is excreted in the urine along with other metabolites. You might find these chapters and articles relevant to this topic.
