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Jan 26, 2024 · Blood acidification may occur with the development of pathological conditions associated with the respiratory system, renal, or gastrointestinal disorders [1–3]. Undesirable changes in acid–base balance, often associated with hypoxia, may develop not only in an adult body, but also in prenatal or early postnatal ontogenesis [ 4 ].
Jun 4, 2020 · Schematic representation of the mechanical forces experienced by endothelial cells due to blood circulation inside the vessels. The blood flow, measured by the volume flow rate Q, causes a shear stress σ shear on the wall. The shear stress depends on the flow rate Q, the blood viscosity η and the vessel radius R.
Acid-base homeostasis maintains systemic arterial pH within a narrow range. Whereas the normal range of pH for clinical laboratories is 7.35-7.45, in vivo pH is maintained within a much narrower range. In clinical and experimental settings, blood pH can vary in response to respiratory or renal impairment. This altered pH promotes changes in ...
- A.C. Celotto, V.K. Capellini, C.F. Baldo, M.B. Dalio, A.J. Rodrigues, P.R.B. Evora
- 2008
The EC apoptosis-accompanied pruned vessels had two important characteristics: 1) most of these segments were longer than those without apoptosis, and 2) the nuclei of adjacent blood vessels occupied both ends . Although EC apoptosis occurs during vessel pruning, it is not absolutely required for the completion of this process [26, 36].
May 24, 2017 · Blood and lymphatic vessels have essential roles in physiology and disease. The endothelial cells that line these vessels specialize to fulfil the needs of the tissue that they pervade. Recent ...
- Michael Potente, Taija Mäkinen
- 2017
The regulation of blood and lymph vessel growth adheres to a law of nature first described by Aristotle [3], which in essence is “form follows function.” In heart, brain, skeletal muscle, and other tissues where blood vessels have primarily a nutritive function, the vasculature grows and regresses in accordance with the metabolic needs of the tissues. Oxygen plays a central role in the ...
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Jun 21, 2023 · Abstract Angiogenesis is the formation of blood vessels from a pre-existing vasculature to provide optimal tissue perfusion. In the adult organism, angiogenesis is also required for its growth and regeneration. Angiogenesis is of great practical importance in terms of its therapeutic regulation: its enhancement can contribute to significant progress in the treatment of ischemic diseases, while ...
