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  1. Feb 13, 2024 · A new study by scientists at Brown University reveals the mechanisms by which Agent Orange affects the brain and how those processes can lead to neurodegenerative diseases. The research shows that exposures to Agent Orange herbicidal chemicals damage frontal lobe brain tissue of laboratory rats with molecular and biochemical abnormalities that are similar to those found in early-stage ...

  2. Feb 14, 2024 · A new study by scientists at Brown University reveals the mechanisms by which Agent Orange affects the brain and how those processes can lead to neurodegenerative diseases. The research shows that ...

  3. Feb 14, 2024 · A new study by scientists at Brown University reveals the mechanisms by which Agent Orange affects the brain and how those processes can lead to neurodegenerative diseases. The research shows that ...

  4. Nov 15, 2018 · This chapter considers the possible effects of toxic exposure to the herbicides used during the Vietnam War and specific clinical conditions associated with the central nervous system (CNS) and the peripheral nervous system (PNS), primarily brain dysfunctions. The COIs are 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram (4-amino-3,5,6 ...

    • 2018/11/15
  5. Mar 6, 2014 · In addition, TCDD has been shown to affect phosphokinase C biochemistry in nerve cells and so could affect the integrity and physiology of nerve cells (Kim et al., 2007; Lee et al., 2007). Cytochrome P450 1A1, the aryl hydrocarbon receptor (AHR), and the AHR nuclear transporter occur in the brain, so TCDD might be likely to exert effects in the brain ( Huang et al., 2000 ).

    • 2014/03/06
  6. Mar 6, 2014 · 10. Effects on Future Generations. Chapter Overview. Based on new evidence and a review of prior studies, the committee for Update 2012 did not find any new significant associations between the relevant exposures and adverse outcomes in future generations. Current evidence supports the findings of earlier studies that.

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  8. May 20, 2024 · Research has revealed associations between Agent Orange exposures and later development of neurodegenerative diseases, and significantly higher rates and earlier onsets of dementia. However, in the absence of a proved causal link, there has been a need for studies that improve understanding of the process by which the herbicide affects the brain.

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