Search results
Apr 13, 2022 · Abstract. Antigen processing and presentation are the cornerstones of adaptive immunity. B cells cannot generate high-affinity antibodies without T cell help. CD4 + T cells, which provide...
- Full Size Image
We would like to show you a description here but the site...
- Metrics
We would like to show you a description here but the site...
- MHC
MHC articles from across Nature Portfolio. Atom; RSS Feed;...
- Full Size Image
Aug 31, 2023 · The body develops immunologic tolerance to these self antigens by triggering apoptosis in self-reactive lymphocytes. Alternately, immature B-lymphocytes with self-reactive B-cell receptors may be stimulated to undergo a new gene rearrangement to make a new receptor that is no longer self-reactive. This process is called receptor editing.
When a lymphocyte encounters its antigen in a peripheral lymphoid organ, the binding of the antigen to the receptors activates the lymphocyte, causing it both to proliferate and to differentiate into an effector cell. An antigen therefore selectively stimulates those cells that express complementary antigen-specific receptors and are thus ...
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
- 2002
- 2002
There are two types of adaptive responses: the cell-mediated immune response, which is controlled by activated T cells, and the humoral immune response, which is controlled by activated B cells and antibodies.
Oct 15, 2016 · Cell signaling pathways regulate much in the life of a cell: from shuttling cargo through intracellular compartments and onto the cell surface, how it should respond to stress, protecting itself from harm (environmental insults or infections), to ultimately, death by apoptosis.
Jun 15, 2007 · During differentiation, apoptosis ensures that lymphocytes express functional antigen receptors and is essential for eliminating lymphocytes with dangerous self-reactive specificities.
People also ask
Which endocytic receptor delivers a captured antigen to a cell?
How do phagocytic cells respond to microbial antigens?
Does rapid B cell apoptosis induced by antigen receptor ligation require FAS (cd95/apo-1?
Why is apoptosis important?
Do lymphocytes respond to foreign antigens?
Feb 24, 2023 · The specificity of the adaptive immune response—its ability to specifically recognize and make a response against a wide variety of pathogens—is its great strength. Antigens, the small chemical groups often associated with pathogens, are recognized by receptors on the surface of B and T lymphocytes.
