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      • The osteoblasts secrete a collagen-proteoglycan matrix that is able to bind calcium salts. Through this binding, the prebone (osteoid) matrix becomes calcified. In most cases, osteoblasts are separated from the region of calcification by a layer of the osteoid matrix they secrete.
  1. Oct 30, 2023 · The osteoblasts differentiate into osteocytes and their processes are enclosed within canaliculi as the matrix becomes calcified. As the bone tissue develops, osteoblasts create a network of trabeculae and spicules. Osteoblasts (histological slide)

    • Parietal

      Parietal bone (Os parietale) The parietal bones are...

    • Tissue

      Epithelial cells nuclei (histological slide) Epithelial...

    • Occipital Bones

      The occipital bone is an unpaired bone which covers the back...

    • Bone

      The high concentration of calcium and phosphate based...

  2. Zone of ossification—bone tissue first emerges in this zone; osteoblasts settle in a layer over the spicules of the calcified cartilage matrix and secrete osteoid, which subsequently transforms into woven bone (and this woven bone is later remodeled into lamellar bone).

  3. The osteoblasts secrete a collagen-proteoglycan matrix that is able to bind calcium salts. Through this binding, the prebone (osteoid) matrix becomes calcified. In most cases, osteoblasts are separated from the region of calcification by a layer of the osteoid matrix they secrete.

    • Scott F Gilbert
    • 2000
    • 2000
  4. Capillaries and osteoblasts from the diaphysis penetrate this zone, and the osteoblasts secrete bone tissue on the remaining calcified cartilage. Thus, the zone of calcified matrix connects the epiphyseal plate to the diaphysis. A bone grows in length when osseous tissue is added to the diaphysis.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
  5. The osteoblasts secrete osteoid, uncalcified matrix, which calcifies (hardens) within a few days as mineral salts are deposited on it, thereby entrapping the osteoblasts within. Once entrapped, the osteoblasts become osteocytes (Figure 1 b).

  6. Apr 9, 2024 · The hyaline cartilaginous precursor of the bones start to form in the 6-8 week embryo; mesenchymal cells differentiate into chondroblasts that secrete extracellular matrix. Chondroblasts become encased in the cartilage matrix and become chondrocytes.

  7. Aug 10, 2023 · The high concentration of calcium and phosphate based minerals throughout the connective tissue is responsible for its hard calcified nature. The histological structure, mode of ossification, cross-sectional appearance, and degree of maturity influences the classification of bony tissue.

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