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  1. Feb 26, 2024 · Here we review studies exploring the long-term effects of adolescent-initiated substance use with structural and microstructural neuroimaging. ... Adolescent Brain Cognitive Development study ...

  2. The refinement and maturation of the central nervous system over this prolonged period, however, makes the adolescent brain highly susceptible to perturbations from acute and chronic drug exposure. Here we review the preclinical literature addressing the long-term consequences of adolescent exposure to common recreational drugs and drugs-of-abuse.

    • Hamed Salmanzadeh, S. Mohammad Ahmadi-Soleimani, Narges Pachenari, Maryam Azadi, Robert F. Halliwell...
    • 2020
  3. Alcohol and marijuana use are common. Recent research has indicated that adolescent substance users show abnormalities on measures of brain functioning, which is linked to changes in neurocognition over time. Abnormalities have been seen in brain structure volume, white matter quality, and activation to cognitive tasks, even in youth with as ...

  4. Jan 3, 2018 · A key strength of the study is that it will enroll enough children—including 800 pairs of twins—to answer questions that require large numbers of subjects, such as whether there are age windows when the brain is particularly vulnerable to use of a given drug. The study intends to reflect the United States's socioeconomic, geographical ...

  5. Oct 6, 2023 · Addiction. Scientific community. Substance use in adolescence is a known risk factor for the development of neuropsychiatric and substance use disorders in adulthood. This is in part due to the ...

  6. Jun 23, 2023 · Landmark study of adolescent brain development renews for additional seven years ... help us understand the effects of substance use, as well as environmental, social ...

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  8. Mar 1, 2020 · The use of addictive substances by adolescents is a growing concern associated with complications such as intoxication and multi-drug abuse. Developmental changes in the brain, including synaptic pruning, a reduction in cortical and subcortical gray volume, maturation of axons and myelination, continue throughout the entire period of adolescence (Andersen, 2003; Schepis et al., 2008).