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    • Image courtesy of researchgate.net

      researchgate.net

      • During endochondral ossification, chondrocytes proliferate, undergo hypertrophy and die; the cartilage extracellular matrix they construct is then invaded by blood vessels, osteoclasts, bone marrow cells and osteoblasts, the last of which deposit bone on remnants of cartilage matrix.
      www.sciencedirect.com/science/article/pii/S135727250700204X
  1. Bones at the base of the skull and long bones form via endochondral ossification. In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondroblasts (cartilage cells) that form the hyaline cartilaginous skeletal precursor of the bones (Figure 6.4.2 a).

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
  2. Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

  3. May 1, 2023 · Endochondral ossification begins with mesenchymal tissue transforming into a cartilage intermediate, which is later replaced by bone and forms the remainder of the axial skeleton and the long bones. Bone ossification, or osteogenesis, is the process of bone formation.

    • Grant Breeland, Margaret A. Sinkler, Ritesh G. Menezes
    • 2023/05/01
    • 2019
  4. Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

  5. May 13, 2022 · Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

  6. Oct 30, 2023 · Bone formation in a developing embryo begins in mesenchyme and occurs through one of two processes: either endochondral or intramembranous osteogenesis (ossification). Intramembranous ossification is characterized by the formation of bone tissue directly from mesenchyme.

  7. Oct 30, 2023 · Endochondral ossification occurs in the long bones around the 6th embryonic week. It involves the formation of hyaline cartilage precursors from aggregated mesenchymal cells , and their subsequent systematic replacement by bone to form the growing skeleton.

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