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  1. Feb 6, 2017 · Mechanisms of damage from fever. There are many pathophysiological mechanisms for the deleterious effects of a fever (Fig. 2): Direct cellular damage: Hyperthermia is directly cytotoxic, becoming significant at 40C. Direct cell death in humans occurs at temperatures of around 41C. Cell death is intimately related to protein denaturation.

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      The effects on the body of a fever This article discusses...

    • Hyperthermia

      This article describes the unintended neurological...

    • Fever

      Does the heat of fever act as an immune stimulant, or does...

  2. Mar 5, 2019 · High fever is characteristic of influenza. It’s actually part of the body’s immune response. We tend to think of a fever as something bad that we want to bring down – it’s very ...

    • Overview
    • Symptoms
    • Causes
    • Complications
    • Prevention

    A fever is a temporary rise in body temperature. It's one part of an overall response from the body's immune system. A fever is usually caused by an infection.

    For most children and adults, a fever may be uncomfortable. But it usually isn't a cause for concern. For infants, however, even a low fever may mean there's a serious infection.

    Body temperatures vary slightly from person to person and at different times of day. The average temperature has traditionally been defined as 98.6 F (37 C). A temperature taken using a mouth thermometer (oral temperature) that's 100 F (37.8 C) or higher is generally considered to be a fever.

    Depending on what's causing a fever, other fever signs and symptoms may include:

    •Sweating

    •Chills and shivering

    •Headache

    •Muscle aches

    Typical body temperature is a balance of heat production and heat loss. An area in the brain called the hypothalamus (hi-poe-THAL-uh-muhs) — also known as your body's "thermostat" — monitors this balance. Even when you're healthy, your body temperature varies slightly throughout the day. It can be lower in the morning and higher in the late afternoon and evening.

    When your immune system responds to disease, the hypothalamus can set your body temperature higher. This prompts complex processes that produce more heat and restrict heat loss. The shivering you might experience is one way the body produces heat. When you wrap up in a blanket because you feel chilled, you are helping your body retain heat.

    Fevers below 104 F (40 C) associated with common viral infections, such as the flu, may help the immune system fight disease and are generally not harmful.

    Fever or elevated body temperature might be caused by:

    •A viral infection

    •A bacterial infection

    Children between the ages of 6 months and 5 years are at increased risk of a seizure that occurs during a fever (febrile seizure). About a third of the children who have one febrile seizure will have another one, most commonly within the next 12 months.

    A febrile seizure may involve loss of consciousness, shaking of limbs on both sides of the body, eyes rolling back or body stiffness. Although alarming for parents, the vast majority of febrile seizures cause no lasting effects.

    If a seizure occurs:

    •Lay your child on the side or stomach on the floor or ground

    •Remove any sharp objects that are near your child

    •Loosen tight clothing

    You may be able to prevent fevers by reducing exposure to infectious diseases. Here are some tips that can help:

    •Get vaccinated as recommended for infectious diseases, such as influenza and COVID-19.

    •Follow public health guidelines for wearing masks and social distancing.

    •Wash your hands often and teach your children to do the same, especially before eating, after using the toilet, after spending time in a crowd or around someone who's sick, after petting animals, and during travel on public transportation.

    •Show your children how to wash their hands thoroughly, covering both the front and back of each hand with soap and rinsing completely under running water.

    •Carry hand sanitizer with you for times when you don't have access to soap and water.

  3. Nov 23, 2020 · Abstract. Although fever is one of the main presenting symptoms of COVID-19 infection, little public attention has been given to fever as an evolved defense. Fever, the regulated increase in the body temperature, is part of the evolved systemic reaction to infection known as the acute phase response. The heat of fever augments the performance ...

    • Sylwia Wrotek, Edmund K LeGrand, Artur Dzialuk, Joe Alcock
    • 2021
  4. Dec 10, 2023 · You wake up in the middle of the night, shivering. You're experiencing a fever — a temporary spike in body temperature. Fevers can arise as the body's defense system fights off an infection, but ...

    • Emily Cooke
  5. Normal body temperature. The average normal body temperature taken orally (under the tongue) is about 37°C (98.6°F). It usually rises during the day from a low of 36.3°C (97.4°F) in the morning to a high of 37.6°C (99.6°F) in the late afternoon. Each child has a normal temperature range that may be different from another child's.

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  7. Fever is one way your child’s body fights an infection. The most common illness in children is infection from a virus. There are thousands of different viruses. Fever can also be caused by an infection with bacteria; Fever itself will not harm your child; How high your child’s temperature is does not tell you how serious your child’s ...

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