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GUIDELINES DEVELOPMENT. In 2010, the Sjögren’s Syndrome Foundation (SSF) enlisted the help of more than 200 professional volunteers nationwide to develop the first ever clinical practice guidelines (CPGs) for SD patients in the United States. The framework for this process is summarized in Fig. 1.
- Pathogenesis and treatment of Sjogren’s syndrome: Review and ...
Sjogren’s syndrome (SS) is a chronic autoimmune disease...
- The Diagnosis and Treatment of Sjögren’s Syndrome - PMC
Sjögren’s syndrome has a wide variety of presentations,...
- Pathogenesis and treatment of Sjogren’s syndrome: Review and ...
- Diagnosis
- Treatment
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Sjogren's syndrome can be difficult to diagnose because the signs and symptoms vary from person to person and can be similar to those caused by other diseases. Side effects of a number of medications also mimic some signs and symptoms of Sjogren's syndrome. Tests can help rule out other conditions and help pinpoint a diagnosis of Sjogren's syndrome...
Treatment for Sjogren's syndrome depends on the parts of the body affected. Many people manage the dry eye and dry mouth of Sjogren's syndrome by using over-the-counter eyedrops and sipping water more frequently. But some people need prescription medications, or even surgical procedures.
Many Sjogren's syndrome symptoms respond well to self-care measures. To relieve dry eyes: 1. Use artificial tears, an eye lubricant or both. Artificial tears — in eyedrop form — and eye lubricants — in eyedrop, gel or ointment form — help relieve the discomfort of dry eyes. You don't have to apply eye lubricants as often as artificial tears. Becaus...
Depending on your symptoms, you might start by seeing your family doctor, dentist or eye doctor. But you might eventually be referred to a doctor who specializes in the treatment of arthritis and other inflammatory conditions (rheumatologist).
Jun 8, 2021 · Immunosuppressant drugs: These are stronger than Plaquenil and actually decrease (or suppress) immune system activity rather than just calm it down. These medicines are called immunosuppressants. They include methotrexate, mycophenolate mofetil, azathioprine, and cyclophosphamide. These are the most common immunosuppressants used for Sjögren’s.
Feb 2, 2023 · Sjogren’s syndrome (SS) is a chronic autoimmune disease accompanied by multiple lesions. The main manifestations include dryness of the mouth and eyes, along with systemic complications (e.g., pulmonary disease, kidney injury, and lymphoma). In this review, we highlight that IFNs, Th17 cell-related cytokines (IL-17 and IL-23), and B cell ...
- 10.3389/fimmu.2023.1127417
- 2023
- Front Immunol. 2023; 14: 1127417.
Sjogren syndrome is a systemic auto-immune disorder characterised by the presence of dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia) as a consequence of lymphocytic infiltration into the lacrimal and salivary glands. Nocturne G, Mariette X. Advances in understanding the pathogenesis of primary Sjogren's syndrome.
May 26, 2017 · Sjögren’s syndrome has a wide variety of presentations, ranging from the local involvement of exocrine glands with keratoconjunctivitis sicca and xerostomia (the leading signs of the disease) to the systemic, extraglandular involvement of multiple organs. Fatigue also markedly worsens the patients’ quality of life.
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Aug 3, 2020 · Sjögren's syndrome is a disabling systemic autoimmune disease characterised by pain, fatigue, and mucosal dryness, with risk of systemic complications (joints, lungs, skin, and peripheral nerves being the most frequently involved) in 30–50% of patients.1 So far, there is no effective immunomodulatory treatment for disease-related systemic complications because most randomised controlled ...
