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Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient investigations....
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- The Three Long-Continued Fevers of New England
Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is...
More than 50 years after the first definition of fever of unknown origin (FUO), it still remains a diagnostic challenge. Evaluation starts with the identification of potential diagnostic clues (PDCs), which should guide further investigations.
Aug 14, 2023 · Epidemiology of fever of unknown origin (FUO) varies based on etiology of fever, age group, geography, environmental exposure, and immune/HIV status. In developing countries, an infectious etiology of FUO is most prevalent whereas, in developed countries, FUO is likely due to non-infectious inflammatory disease.
- Ilona Brown, Nancy A. Finnigan
- 2023/08/14
- 2021
Feb 1, 2022 · Human immunodeficiency virus-associated fever of unknown origin was defined as fever of more than 4 weeks duration for outpatients or more than 3 days duration in the hospital. Fever of 38.3°C (100.9°F) or higher on at least 3 occasions suggested.
- William F. Wright, Catharina M. Mulders-Manders, Paul G. Auwaerter, Chantal P. Bleeker-Rovers
- 2021
Jan 16, 2011 · Overall, 12% to 35% of patients die from FUO-related causes. 4,26,36,37 Patients with a final diagnosis of malignancy have the highest mortality, with 52% to 100% of patients dying within 5 years of diagnosis. Mortality is much lower in patients with infection as the cause of FUO (8%-22%).
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What causes fever of unknown origin (FUO)?
Jul 9, 2024 · Fever of unknown origin (FUO) is body temperature ≥ 38.3° C (≥ 101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or with abnormalities on common tests such as chest radiograph, urinalysis, or blood cultures.
