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  1. Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient investigations....

  2. Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is...

  3. Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous. Noninfectious Inflammatory Causes of FUO.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  4. Feb 1, 2022 · Human immunodeficiency virus-associated fever of unknown origin was defined as fever of more than 4 weeks duration for outpatients or more than 3 days duration in the hospital. Fever of 38.3°C (100.9°F) or higher on at least 3 occasions suggested.

    • William F. Wright, Catharina M. Mulders-Manders, Paul G. Auwaerter, Chantal P. Bleeker-Rovers
    • 2021
  5. Nov 28, 2023 · Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin (FUO). However, most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  6. Fever of unknown origin (FUO) is a clinical and diagnostic challenge in routine medical practice and the potential causes of FUO may involve more than 200 diseases [1, 2]. Apart from diarrheal diseases, respiratory infections, and skin lesions, FUO is one of the most common health problems in travelers [ 3 , 4 ].

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  8. Jun 10, 2024 · Classic fever of unknown origin (FUO) was first robustly studied in 1961, with subsequent modifications in definitions (Table 1) [1, 2]. These FUO definitions require an illness of ≥3 weeks duration and temperatures of ≥38.3°C (≥100.9°F) on several occasions [1, 2].

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