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Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient investigations....
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Fever of unknown origin (FUO) was originally defined by Petersdorf and Beeson as an illness of more than 3 weeks’ duration, with fever greater than 38.3 °C (101 °F) on several occasions, the cause of which is uncertain after 1 week of in-hospital investigations.
Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is...
Nov 10, 2024 · One-fourth of patients who report being febrile for ≥ 6 months have no true fever or underlying disease. Instead, the usual normal circadian variation in temperature (temperature 0.5–1.0°C higher in the afternoon than in the morning) is interpreted as abnormal
Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous.
- Ilona Brown, Nancy A. Finnigan
- 2023/08/14
- 2021
In adults, infections (25–40% of cases) and cancer (25–40% of cases) account for the majority of FUOs. In children, infections are the most common cause of FUO (30–50% of cases) and cancer a rare cause (5–10% of cases).
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Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, cou-pled with an unrevealing diagnostic workup. The diferential diagnosis is...
