Search results
Jan 30, 2015 · Activation syndrome may be related to self-injury via diminished serotonergic activity which could compromise the ability of patients to self-regulate their behavior [9, 19]. The activation-related disinhibition may also lead to impulse control problems [ 27 ].
- Maya Amitai, Alon Chen, Alon Chen, Abraham Weizman, Alan Apter
- 2015
Despite the recognition of antidepressant-related activation as a risk factor for medication discontinuation and suicidality, the activation syndrome lacks a clear definition. 2,14 Currently, several symptoms are considered to be activation-related adverse events: disinhibition, impulsivity, insomnia, restlessness, hyperactivity, and irritability. Moreover, these symptoms frequently co-occur.
Apr 2, 2024 · However, during the 12-week follow-up, 14% of participants experienced an SE and 9% had a nonsuicidal self-injury event. The median time to an SE was 3 weeks. 5 Like TORDIA contrary to TADS, the Adolescent Depression Antidepressants and Psychotherapy Trial (ADAPT) in the United Kingdom 7 did not find evidence for SSRI-associated treatment-emergent suicidality or the protective effects of CBT.
It is unclear if AC-AEs are related to akathisia, which may have a similar clinical presentation. Moreover, it is hypothesized in one case report that activation is related to self-injurious behavior via serotonergic-mediated effects that could compromise a patient's ability to self-regulate their behavior (King et al. 1991).
- Shauna P. Reinblatt, Susan dosReis, John T. Walkup, Mark A. Riddle
- 10.1089/cap.2008.040
- 2009
- 2009/04
Abstract. Evidence from diverse literatures supports the viewpoint that two modes of self-regulation exist, a lower-order system that responds quickly to associative cues of the moment and a higher-order system that responds more reflectively and planfully; that low serotonergic function is linked to relative dominance of the lower-order system; that how dominance of the lower-order system is ...
Feb 2, 2010 · The initial version of the TE-ASAP—from which the present data were collected—consists of the following subscales 1: (a) Irritability (12 items), (b) Akathisia, Hyperkinesis, and Somatic Anxiety (10 items), (c) Disinhibition and Impulsivity (7 items), (d) Mania (10 items), and (e) Self-injury, Suicidality, and Harm to Others (8 items). For each item, parents were asked to separately rate ...
People also ask
Is activation syndrome related to self-injury?
How is activation syndrome defined?
What is the difference between activation syndrome and energizing phenomena?
What is the prevalence of activation syndrome?
Do SSRIs cause activation syndrome?
What is the difference between activation syndrome and akathisia (psychomotor restlessness)?
Apr 1, 2024 · Activation syndrome has received little attention, which is why it can be overlooked. This is due to the lack of a precise definition and the possibility of confusing it with a worsening of the underlying psychiatric disorder or mania triggered by the antidepressants. In these circumstances, activation syndrome is a serious adverse event.
