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  1. The effects of high altitude on humans are mostly the consequences of reduced partial pressure of oxygen in the atmosphere. The medical problems that are direct consequence of high altitude are caused by the low inspired partial pressure of oxygen, which is caused by the reduced atmospheric pressure, and the constant gas fraction of oxygen in atmospheric air over the range in which humans can ...

  2. Dec 28, 2021 · The ISS is in a low Earth orbit (LEO) at an altitude of approximately 400 km and with an orbital inclination of 51.6°. Higher altitudes are less protected by the geomagnetic field against charged particles [ 8 ].

    • 10.3390/biomedicines10010059
    • 2022/01
    • Biomedicines. 2022 Jan; 10(1): 59.
  3. Jun 16, 2020 · However, in a microgravity environment, free from the Earth's gravitational gradient, the body experiences a uniform arterial pressure throughout, which reduces the physiological need for the body's blood pressure regulatory mechanisms and consequently decreases the cardiac workload. 7, 8 Within the first 24 hours of spaceflight, astronauts commonly experience a decrease in central venous ...

    • Nicholas A Vernice, Cem Meydan, Ebrahim Afshinnekoo, Christopher E Mason
    • 10.1093/pcmedi/pbaa022
    • 2020
    • Precis Clin Med. 2020 Dec; 3(4): 284-291.
  4. Jun 8, 2021 · However, the literature shows no evidence of increased incidence of acute myocardial ischemic events at low and moderate altitude. 60, 72, 81, 82 In nine men with coronary artery disease, clinical or electrocardiographic signs of ischemia occurred at lower workloads at 3100 m than at 1600 m, although heart rate and heart rate x systolic blood pressure (rate pressure product, RPP) at the onset ...

    • Robert T Mallet, Johannes Burtscher, Jean-Paul Richalet, Gregoire P Millet, Martin Burtscher
    • 10.2147/VHRM.S294121
    • 2021
    • Vasc Health Risk Manag. 2021; 17: 317-335.
  5. Very low Earth orbit. Very low Earth orbit is a range of orbital altitudes below 400 km (250 mi), and is of increasing commercial importance in a variety of scenarios and for multiple applications, in both private and government satellite operations. Applications include earth observation, radar, infrared, weather, telecommunications, and rural ...

  6. Oct 2, 2023 · Recommendations to avoid high altitude apply only to patients with uncontrolled or severe hypertension (systolic blood pressure >180 mmHg and/or diastolic blood pressure >110 mmHg). Pulmonary ...

  7. Jun 12, 2018 · Even in elite athletes, high levels of fitness are not protective for altitude sickness. There’s some evidence those who experience the worst symptoms have a low ventilatory response to hypoxia.

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