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Definition. systemic autoimmune d/o that affects the EXOCRINE GLANDS--primarily the lacrimal and salivary glands. Primary Sjogren's syndrome. occurs in isolation. Secondary Sjogren's syndrome. occurs w/ another Rheumatic dz. 30-50% = RA. 10-25% = SLE.
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primary: alone secondary: associated with other autoimmune diseases (Hashimoto's) Pathophysiology inflammatory destruction of the exocrine gland characterized by focal lymphocytic infiltration of the exocrine glands
- Overview
- Symptoms
- Causes
- Risk Factors
- Complications
Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually...
The two main symptoms of Sjogren's syndrome are: 1. Dry eyes.Your eyes might burn, itch or feel gritty — as if there's sand in them. 2. Dry mouth.Your mouth might feel like it's full of cotton, making it difficult to swallow or speak. Some people with Sjogren's syndrome also have one or more of the following: 1. Joint pain, swelling and stiffness 2...
Sjogren's syndrome is an autoimmune disorder. Your immune system mistakenly attacks your body's own cells and tissues. Scientists aren't certain why some people develop Sjogren's syndrome. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bact...
Sjogren's syndrome typically occurs in people with one or more known risk factors, including: 1. Age.Sjogren's syndrome is usually diagnosed in people older than 40. 2. Sex.Women are much more likely to have Sjogren's syndrome. 3. Rheumatic disease.It's common for people who have Sjogren's syndrome to also have a rheumatic disease — such as rheumat...
The most common complications of Sjogren's syndrome involve your eyes and mouth. 1. Dental cavities.Because saliva helps protect the teeth from the bacteria that cause cavities, you're more prone to developing cavities if your mouth is dry. 2. Yeast infections.People with Sjogren's syndrome are much more likely to develop oral thrush, a yeast infec...
Sjögren's syndrome (SS) is the third-most common rheumatic autoimmune disorder, behind rheumatoid arthritis and systemic lupus erythematosus. [19] There are no geographical differences in the rates of SS. [97] Sjögren's syndrome has been reported in all areas of the world, although regional rates have not been well studied. [97] [98]
Overview. Sjögren's syndrome is a chronic autoimmune disease in which the body's immune system mistakenly attacks its own moisture-producing glands. As a result, people with this condition usually have dry eyes and a dry mouth. Sjögren's syndrome may also cause dryness of the skin or vagina and may affect other organs, such as the lungs ...
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Jul 19, 2024 · Sjögren's (pronounced show-grins) syndrome is an autoimmune disorder in which the system that normally fights infection and disease in the body mistakenly attacks its own healthy tissues. In Sjögren's syndrome, the immune system attacks and destroys the glands that make tears and saliva. The main symptoms of Sjögren's syndrome are: It can ...
