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  1. This can cause cells that should be resting to divide and grow out of control, which can lead to cancer. Our bodies are made up of trillions of cells grouped to form tissues and organs. Genes inside the nucleus of each cell tell it when to grow, work, divide and die.

    • Cell Changes and Cancer
    • Genes and Cell Division
    • Gene Changes Within Cells
    • How Mutations Happen
    • Related Information

    All cancers begin in cells. Our bodies are made up of more than a hundred million million (100,000,000,000,000) cells. Cancer starts with changes in one cell or a small group of cells. Usually, we have just the right number of each type of cell. This is because cells produce signals to control how much and how often the cells divide. If any of thes...

    Different types of cells in the body do different jobs. But they are similar. All cells have a control centre called a nucleus. Inside the nucleus are chromosomes made up of thousands of genes. Genes contain long strings of DNA (deoxyribonucleic acid), which are coded messages that tell the cell how to behave. Each gene is an instruction that tells...

    Genes make sure that cells grow and make copies (reproduce) in an orderly and controlled way. They keep the body healthy. Sometimes a change happens in the genes when a cell divides. This is a mutation. It means that a gene has been damaged or lost or copied too many times. Mutations can happen by chance when a cell is dividing. Some mutations mean...

    Mutations can happen by chance when a cell is dividing. They can also be caused by the processes of life inside the cell. Or by things coming from outside the body, such as the chemicals in tobacco smoke. And some people can inherit faults in particular genes that make them more likely to develop a cancer. Some genes get damaged every day and cells...

    You can read about: 1. how cells and tissues grow 2. cancer cells 3. genes, DNA and cancer 4. how cancers grow Next review due: 6 October 2026

  2. Oct 11, 2021 · Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and multiply (through a process called cell division) to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place.

  3. One of the fundamental features of cancer is tumor clonality, the development of tumors from single cells that begin to proliferate abnormally. The single-cell origin of many tumors has been demonstrated by analysis of X chromosome inactivation (Figure 15.2).

    • Geoffrey M Cooper
    • 2000
    • 2000
  4. One such understanding is that cancer cells are indigenous cells—abnormal cells that arise from the body's normal tissues. Furthermore, virtually all malignant tumors are monoclonal in origin, that is, derived from a single ancestral cell that somehow underwent conversion from a normal to a cancerous state.

    • 2007
  5. Cancer can start in any part of the body. When cancer cells form a lump or growth, it is called a cancerous tumour. A tumour is cancerous when it: Cancer that spreads from the first place it started (called the primary tumour) to a new part of the body is called metastatic cancer.

  6. Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, go beyond their usual boundaries to invade adjoining parts of the body and/or spread to other organs. The latter process is called metastasizing and is a major cause of death from cancer.

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